Instgra 50Mg Tablets

Introduction to Instgra 50Mg Tablets

Instgra 50 mg tablet is a medication that contains the active ingredient dolutegravir. It belongs to the class of drugs known as integrase strand transfer inhibitors (INSTIs), and it is primarily used for the treatment of HIV-1 infection. Dolutegravir works by inhibiting the action of the integrase enzyme, which is essential for the integration of viral DNA into the host cell’s DNA. This mechanism prevents the virus from replicating and spreading within the body.

Instgra 50 mg, manufactured by Emcure Pharmaceuticals, is a groundbreaking medication used in the management of HIV (Human Immunodeficiency Virus) infection. The active ingredient in Instgra 50 mg is dolutegravir, a potent integrase inhibitor that plays a crucial role in suppressing the replication of the virus within the body.

Uses of Instgra 50mg

Instgra 50 mg tablet, which contains the active ingredient dolutegravir, is primarily used for the treatment of HIV-1 infection. Dolutegravir is classified as an integrase strand transfer inhibitor (INSTI) and plays a crucial role in managing HIV infection by interfering with the virus’s replication process. Here are the main uses of Instgra 50 mg tablet:

• Treatment of HIV-1 Infection
  
• Adults infected with HIV-1.
• Pediatric patients (weighing at least 30 kg or aged 6 years and older) with HIV-1 infection.

The medication is used in combination with other antiretroviral agents to form a comprehensive treatment regimen. This approach helps control the viral load, maintain immune function, and slow down the progression of the disease.

Important Points to Note:

• Instgra 50 mg tablet is not a cure for HIV-1 infection. It is used to manage the infection and improve the quality of life of individuals living with HIV.
• The medication’s effectiveness is enhanced when it is used in combination with other antiretroviral drugs as prescribed by a healthcare provider.
• Early and consistent treatment with effective antiretroviral medications like Instgra can help suppress viral replication, increase CD4 cell counts, and reduce the risk of opportunistic infections.

Before initiating treatment with Instgra 50 mg tablets, it’s essential to consult a healthcare provider who specializes in HIV care. They will assess your medical history, conduct appropriate tests, and tailor a treatment plan that addresses your specific needs and circumstances. Adhering to the prescribed treatment regimen and attending regular medical check-ups are essential components of effectively managing HIV-1 infection.

How Does Instgra 50 Works?  

Instgra 50 mg tablet contains the active ingredient dolutegravir, which belongs to the class of drugs known as integrase strand transfer inhibitors (INSTIs). These drugs are used to treat HIV-1 infection by targeting a specific enzyme called integrase that plays a crucial role in the replication process of the human immunodeficiency virus (HIV).

• Inhibition of Integrase Enzyme
• Blocking Viral Integration
• Inhibition of Viral Replication
• Reduction in Viral Load
• Maintenance of Immune Function

Side Effects of Instgra 50mg

Common Side Effects

• Headache
• Insomnia
• Fatigue
• Nausea
• Diarrhea
• Abdominal Pain
• Rash
• Changes in Liver Enzymes

Serious Side Effects

• Hypersensitivity Reaction
• Severe Skin Reactions
• Liver Problems
• Lactic Acidosis
• Changes in Mood or Behavior
• Severe Skin Rash
• Immune Reconstitution Inflammatory Syndrome (IRIS)

Rare Side Effects

• Pancreatitis
• Hepatic Events
• Increased Blood Sugar Levels
• Changes in Body Fat Distribution
• Rhabdomyolysis
• Neuropsychiatric Symptoms
• Hypersensitivity to Sulfonamide Medications
• Immune Reconstitution Inflammatory Syndrome (IRIS)

How To Manage Side Effects? 

• Communication with Healthcare Provider
• Follow Dosage Instructions
• Stay Hydrated
• Take with Food
• Adherence to Treatment
• Healthy Diet and Lifestyle
• Monitor Symptoms
• Over-the-Counter Remedies
• Skin Care
• Rest and Sleep
• Stress Management
• Report Severe Side Effects

Warning & Precautions 

• Hypersensitivity Reactions
• Liver Function
• Immune Reconstitution Inflammatory Syndrome (IRIS)
• Lactic Acidosis
• Pregnancy and Breastfeeding
• Children and Adolescents
• Renal Impairment
• Bone Health
• Drug Interactions
• Lipid Elevations
• Changes in Mood or Behavior
• Sulfonamide Allergy

Safety Advice

• Prescription Only
• Follow Healthcare Provider’s Instructions
• Combination Therapy
• Allergies and Hypersensitivity
• Pregnancy and Breastfeeding
• Renal Function
• Liver Function
• Children and Adolescents
• Lipid Monitoring
• Driving and Operating Machinery
• Emergency Contact
• Medication Storage

Frequently Asked Questions

1. What is Instgra 50 mg used for?

Ans. Instgra 50 mg tablets are used for the treatment of HIV-1 infection in both adult patients and pediatric patients weighing at least 30 kg (approximately 66 LBS) or aged 6 years and older.

2. How does Instgra 50 mg work?

Ans. Instgra 50 mg contains the active ingredient dolutegravir, which is an integrase strand transfer inhibitor (INSTI). It works by inhibiting the integrase enzyme of HIV, preventing the virus from integrating its genetic material into the host cell’s DNA and thereby reducing viral replication.

3. Is Instgra 50 mg a cure for HIV?

Ans. No, Instgra 50 mg is not a cure for HIV-1 infection. It is used to manage the infection and control viral replication, allowing individuals to lead healthier lives and reduce the risk of transmission.

4. Can I take Instgra 50 mg with food?

Ans. Instgra 50 mg tablets can be taken with or without food, as directed by your healthcare provider. Some individuals may find it more comfortable to take it with food to reduce the likelihood of stomach upset.