Megagliptin MF 20/500mg Tablets

Introduction to Megagliptin MF 20/500 mg Tablets

Megagliptin MF 20/500mg Tablets is a combination of Metformin and Teneligliptin which belongs to the group of medicines called Antidiabetic agents. It is used to treat Type II diabetes mellitus among patients when diet, exercise and treatment with other conventional medicines does not result in adequate control on blood glucose levels.

Type II diabetes mellitus is a chronic disease characterized by abnormally high levels of glucose in the blood. It is caused due to inadequate production of a hormone called insulin (produced by pancreas to metabolize glucose) in the body or due to inadequate sensitivity of body cells to the actions of insulin.

Before taking Megagliptin MF 20/500mg Tablets inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have low potassium levels in blood or are severely dehydrated due to excessive vomiting or diarrhea recently. Megagliptin MF 20/500mg Tablets are manufactured by Aristo Pharma.

During therapy with Megagliptin MF 20/500mg Tablets, your doctor might regularly monitor your blood sugar levels and kidney functions to avoid the risk of unwanted side effects. He/she might also ask you to make certain lifestyle changes such as following a healthy diet, regular physical exercise and quitting alcohol consumption to achieve better results.

Uses of Megagliptin MF 20/500mg

• Improves Blood Sugar Control
• Dual Mechanism of Action
• Reduces Risk of Complications
• Weight Neutral or Modest Weight Loss

How Does Megagliptin MF 20/500 Works?

Megagliptin MF 20/500mg Tablets is an antidiabetic medicine. It contains two medicines namely metformin and teneligliptin. Metformin makes the body more sensitive to insulin (a hormone involved in glucose metabolism). This helps our body cells to utilize more amount of the circulating blood glucose. Additionally, it can stop glucose production by the liver and reduces its absorption in the body.

Teneligliptin controls blood sugar levels by blocking the actions of an enzyme called Dipeptidyl Peptidase (DPP)-4 that reduces insulin secretion in the body. Collectively, Megagliptin MF 20/500mg Tablets controls blood sugar levels and improve glycemic control in patients with type II diabetes.

Side Effects of Megagliptin MF 20/500

• Hypoglycemia (low blood sugar)
• Nausea, vomiting
• Flatulence
• Diarrhea
• Constipation
• Stomach ain, loss of appetiteP
• Headache
• Dizziness
• Changes in taste

How to Manage Side Effects?

• Contact Your Healthcare Provider
• Follow Prescribed Dosage
• Timing and Administration
• Stay Hydrated
• Monitor Blood Sugar Levels
• Avoid Alcohol and Certain Foods
• Compliance with Medication

Warnings & Precautions

1. Kidney Function:

• Use with caution in patients with impaired kidney function, especially due to the risk of lactic acidosis from metformin.

2. Liver Disease:

• Avoid in patients with severe liver dysfunction, as it can increase the risk of adverse effects.

3. Heart Conditions:

• Use carefully in patients with heart failure or a history of heart disease.

4. Lactic Acidosis Risk:

• Rare but serious; symptoms include muscle pain, weakness, difficulty breathing, abdominal pain, or drowsiness.

5. Hypoglycemia:

• Alone, the risk is low—but if combined with other drugs (like insulin or sulfonylureas), hypoglycemia risk increases.

6. Surgery or Imaging Tests:

• Metformin should be temporarily stopped before any major surgery or contrast dye procedures (CT scans, MRIs).

7. Pancreatitis Risk:

• Rare cases linked to DPP-4 inhibitors like Teneligliptin. Report symptoms like severe abdominal pain immediately.

8. Pregnancy & Breastfeeding:

• Use only if clearly needed; consult your doctor. Safety in pregnancy and lactation is not well established.

9. Elderly Patients:

• Monitor kidney function regularly, as they are more prone to side effects.

Storage

• Store below 30°C room temperature.
• Keep in original packaging tightly.
• Protect from direct sunlight exposure.
• Store in a dry place.
• Keep away from moisture sources.
• Do not freeze the medicine.
• Keep out of children’s reach.
• Avoid storing near strong odors.

Frequently Asked Questions

1. Can I drink alcohol with this medicine?

Avoid alcohol. It increases the risk of lactic acidosis and worsens sugar control.

2. Can I stop the medication suddenly?

No. Stopping suddenly can lead to uncontrolled blood sugar. Consult your doctor.

3. What should I do if I miss a dose?

Take it as soon as remembered. Skip if it’s near the next dose. Don’t double dose.

4. How should I take this medicine?

Take it orally with meals to reduce stomach upset. Follow your doctor’s instructions.