Introduction to Actiglipt M 20/500 mg Tablet
Actiglipt M 20/500mg Tablet is a combination of Metformin and Teneligliptin which belongs to the group of medicines called Antidiabetic agents. It is used to treat Type II diabetes mellitus among patients when diet, exercise and treatment with other conventional medicines does not result in adequate control on blood glucose levels.
Type II diabetes mellitus is a chronic disease characterized by abnormally high levels of glucose in the blood. It is caused due to inadequate production of a hormone called insulin (produced by pancreas to metabolize glucose) in the body or due to inadequate sensitivity of body cells to the actions of insulin.
Before taking Actiglipt M 20/500mg Tablet T inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have low potassium levels in blood or are severely dehydrated due to excessive vomiting or diarrhea recently.
During therapy with Actiglipt M 20/500mg Tablet, your doctor might regularly monitor your blood sugar levels and kidney functions to avoid the risk of unwanted side effects. He/she might also ask you to make certain lifestyle changes such as following a healthy diet, regular physical exercise and quitting alcohol consumption to achieve better results.
Actiglipt M 20/500mg Tablet is not recommended for use in patients with severe uncontrollable diabetes. It is also not suitable for use in patients with alcoholism and in patients with severe systemic infections.
Consult your doctor before taking Actiglipt M 20/500mg Tablet if you are pregnant or breastfeeding. The most common side effects of taking Actiglipt M 20/500mg Tablet are low blood sugar levels, stomach upset, constipation, flatulence and altered taste sensations. Consult your doctor if they bother you.
Uses of Actiglipt M 20/500 mg
- Treats Type II diabetes mellitus
How Does Actiglipt M 20/500 Works?
Actiglipt M 20/500mg Tablet is an antidiabetic medicine. It contains two medicines namely metformin and teneligliptin. Metformin makes the body more sensitive to insulin (a hormone involved in glucose metabolism). This helps our body cells to utilize more amount of the circulating blood glucose. Additionally, it can stop glucose production by the liver and reduces its absoprtion in the body.
Teneligliptin controls blood sugar levels by blocking the actions of an enzyme called dipeptidyl peptidase (DPP)-4 that reduces insulin secretion in the body. Collectively, Actiglipt M 20/500mg Tablet controls blood sugar levels and improve glycemic control in patients with type II diabetes.
Side Effects of Actiglipt M 20/500
Common Side Effects
- Nausea
- Diarrhea
- Stomach upset or abdominal pain
- Loss of appetite
- Headache
- Dizziness
- Fatigue or weakness
Serious Side Effects
- Severe allergic reactions (e.g., hives, difficulty breathing, swelling of the face, lips, tongue, or throat)
- Lactic acidosis (rare but serious condition; symptoms may include rapid breathing, muscle pain, stomach discomfort, unusual weakness or tiredness)
- Pancreatitis (inflammation of the pancreas; symptoms may include severe abdominal pain, nausea, vomiting)
Rare Side Effects
- Blood disorders (e.g., changes in blood cell counts)
- Allergic skin reactions (e.g., rash, itching)
- Hypersensitivity reactions
- Hepatitis (inflammation of the liver)
- Stevens-Johnson syndrome (a severe skin reaction)
- Angioedema (swelling of the face, lips, tongue, or throat)
- Acute kidney injury
- Photosensitivity reactions (increased sensitivity to sunlight)
- Taste disturbances
- Abnormal liver function tests
Dosage of Actiglipt M 20/500
- The typical starting dose is one tablet of Actiglipt M 20/500 once daily.
- The tablet should be taken with meals to reduce the risk of stomach upset.
- Your doctor may adjust the dosage based on your blood sugar levels and response to the medication.
- The maximum recommended dose is one tablet of Actiglipt M 20/500 twice daily (morning and evening) with meals.
- Do not exceed the recommended dosage unless instructed by your healthcare provider.
- If you miss a dose, take it as soon as you remember, but do not double the dose if it’s almost time for the next scheduled dose.
Other Dosages of Actiglipt M 20/500mg Tablet
How to Manage Side Effects?
- Contact Your Healthcare Provider
- Stick to the Prescribed Dosage.
- Take With Meals
- Stay Hydrated
- Monitor Blood Sugar Levels
- Report Severe Side Effects
- Follow Lifestyle Recommendations
- Keep Track of Symptoms
- Discuss Alternatives
Warning & Precautions
- Allergic Reactions
- Lactic Acidosis
- Pancreatitis
- Hypoglycemia
- Kidney Function
- Liver Function
- Heart Failure
- Pregnancy and Breastfeeding
- Surgery and Imaging Studies
- Other Medications
- Pediatric Use
- Elderly Patients
- Alcohol Use
Safety Advice
- Prescription Only: Actiglipt M 20/500 is a prescription medication. It should only be used under the guidance and supervision of a qualified healthcare professional.
- Follow Dosage Instructions: Take Actiglipt M 20/500 exactly as prescribed by your doctor. Do not alter the dosage or stop the medication without consulting your healthcare provider.
- Take With Meals: To reduce the risk of stomach upset, take Actiglipt M 20/500 with meals.
- Monitor Blood Sugar: Regularly monitor your blood sugar levels as directed by your doctor to ensure the medication is effectively managing your diabetes.
- Inform About Medical History: Provide your doctor with a detailed medical history, including any existing medical conditions, allergies, liver or kidney problems, heart issues, or history of pancreatitis.
- Report Side Effects: If you experience any side effects while taking Actiglipt M 20/500, inform your doctor promptly. This includes common, rare, and severe side effects.
- Allergic Reactions: If you have a known allergy to Sitagliptin, Metformin, or any components of Actiglipt M 20/500, inform your doctor immediately.
- Lifestyle Measures: Follow a healthy lifestyle, including a balanced diet, regular physical activity, and avoiding smoking and excessive alcohol consumption. These measures can complement the effects of Actiglipt M 20/500 in managing diabetes.
- Kidney Function: If you have kidney problems, your doctor may adjust the dosage of Actiglipt M 20/500 or consider an alternative treatment.
Frequently Asked Questions
1. What is Actiglipt M 20/500, and what is it used for?
Ans. Actiglipt M 20/500 is a fixed-dose combination medication used to manage type 2 diabetes in adults. It contains Sitagliptin (a DPP-4 inhibitor) and Metformin. Sitagliptin helps increase insulin secretion and reduce glucose production, while Metformin improves insulin sensitivity and lowers glucose production in the liver.
2. How does Actiglipt M 20/500 work?
Ans. Actiglipt M 20/500 combines the effects of Sitagliptin and Metformin to help lower blood sugar levels and improve diabetes management.
3. How should I take Actiglipt M 20/500?
Ans. Follow your doctor’s instructions regarding the dosage and timing of Actiglipt M 20/500. It is typically taken orally with meals to reduce stomach upset.
4. Can I take Actiglipt M 20/500 with other diabetes medications?
Ans. Actiglipt M 20/500 can be used alone or in combination with other diabetes medications, as determined by your healthcare provider.
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