Actiglipt M 1000 mg

Introduction to Actiglipt M 1000 Tablets

Actiglipt M 1000 Tablet is a combination of Metformin and Teneligliptin which belongs to the group of medicines called Antidiabetic agents. It is used to treat Type II diabetes mellitus among patients when diet, exercise and treatment with other conventional medicines does not result in adequate control on blood glucose levels.

Type II diabetes mellitus is a chronic disease characterized by abnormally high levels of glucose in the blood. It is caused due to inadequate production of a hormone called insulin (produced by pancreas to metabolize glucose) in the body or due to inadequate sensitivity of body cells to the actions of insulin.

Actiglipt M 1000 Tablet is not recommended for use in patients with severe uncontrollable diabetes. It is also not suitable for use in patients with alcoholism and in patients with severe systemic infections.

This medicine is manufactured by Akesiss Pharma. Akesiss Pharma Pvt Ltd company is incorporated as a Private Limited Company in the year 2008.

Uses of Actiglipt M 1000

• Manages type 2 diabetes
• Controls blood sugar
• Improves insulin sensitivity
• Reduces glucose production
• Enhances insulin secretion

How Does Actiglipt M 1000 Work?

Actiglipt M 1000 Tablets is an antidiabetic medicine. It contains two medicines namely metformin and teneligliptin. Metformin makes the body more sensitive to insulin (a hormone involved in glucose metabolism). This helps our body cells to utilize more amount of the circulating blood glucose. Additionally, it can stop glucose production by the liver and reduces its absorption in the body.

Teneligliptin controls blood sugar levels by blocking the actions of an enzyme called dipeptidyl peptidase (DPP)-4 that reduces insulin secretion in the body. Collectively, Actiglipt M 1000 Tablets controls blood sugar levels and improve glycemic control in patients with type II diabetes.

Side Effects of Actiglipt M 1000

• Nausea
• Diarrhea
• Stomach upset or abdominal discomfort
• Headache
• Dizziness
• Hypoglycemia
• Upper respiratory tract infections
• Skin rash or itching

Dosage of Actiglipt M 1000

• The typical starting dose of Actiglipt M 1000 is one tablet taken orally once daily.
• The medication is usually taken with meals to reduce the risk of stomach upset.
• The dosage may be adjusted by your healthcare provider based on your individual response and blood sugar levels.
• Your doctor will determine the most appropriate dosage for you based on factors such as your medical history, kidney function, and other medications you may be taking.
• Do not exceed the prescribed dose unless instructed by your healthcare provider.

Strengths and Variants

• Actiglipt M 20/500mg
• Actiglipt M 20mg

How to Manage Side Effects? 

• Take medication with food.
• Stay hydrated throughout the day.
• Monitor blood sugar regularly.
• Avoid alcohol while taking medication.
• Report severe symptoms immediately.
• Follow prescribed dosage strictly.
• Discuss concerns with your doctor.

Warnings & Precautions

• When combined with other antidiabetic drugs like sulfonylureas or insulin, it may cause low blood sugar. Monitor glucose levels regularly.
• A rare but serious side effect. Watch for symptoms like muscle pain, breathing difficulty, drowsiness, or abdominal discomfort.
• Metformin is excreted through the kidneys. Regular renal function tests are essential, especially in elderly or dehydrated patients.
• Use with care in patients with liver disorders, as it may worsen the risk of side effects.
• This medicine is only for type 2 diabetes. Do not use it for type 1 or diabetic ketoacidosis.
• Stop the medicine temporarily before surgery or radiologic studies involving contrast agents to avoid complications.

Storage

• Store at room temperature between 15°C to 30°C (59°F to 86°F).
• Keep in a cool, dry place, away from moisture and humidity.
• Protect from direct sunlight and heat to maintain tablet stability.
• Do not refrigerate or freeze the medication.
• Store in original packaging until use to preserve quality.
• Keep out of reach of children and pets to prevent accidental ingestion.
• Dispose of expired tablets properly, following your pharmacist’s or local disposal guidelines.

Frequently Asked Questions