Introduction to Accuglim MP 1mg Tablet
Accuglim MP 1mg is a combination anti-diabetic medication that contains Glimepiride (1mg), Pioglitazone, and Metformin. This triple-drug formula is used to manage type 2 diabetes mellitus in adults when diet, exercise, and monotherapy with individual agents are insufficient to control blood sugar levels effectively.
Glimepiride is a sulfonylurea that stimulates the pancreas to release insulin. Metformin works by reducing glucose production in the liver and improving insulin sensitivity. Pioglitazone belongs to the thiazolidinedione class and helps the body use insulin more effectively by acting on fat and muscle cells.
This combination provides a synergistic effect to maintain better glycemic control and prevent diabetes-related complications. It should be taken with meals as prescribed by a doctor and is usually part of a broader treatment plan that includes dietary changes and physical activity.
What Are The Uses of Accuglim MP 1mg?
Here are some primary uses of Accuglim MP 1mg Tablets:
- Controls Type 2 Diabetes Mellitus
- Improves insulin sensitivity
- Reduces liver glucose production
- Stimulates insulin secretion
How Does Accuglim MP 1mg Tablets Works?
Accuglim MP 1mg Tablet works through a triple mechanism to control blood sugar levels in type 2 diabetes. Glimepiride stimulates the pancreas to release more insulin, helping lower blood sugar after meals. Metformin reduces glucose production in the liver and increases insulin sensitivity, allowing better sugar absorption by the cells.
Pioglitazone, the third component, works by improving the body’s response to insulin in fat and muscle tissues. Together, these three agents provide comprehensive blood sugar control by targeting different aspects of glucose metabolism, making it effective when monotherapy is insufficient.
Side Effects of Accuglim MP 1mg Tablet
- Nausea or vomiting
- Stomach discomfort or indigestion
- Diarrhea or flatulence
- Weight gain
- Headache or dizziness
Dosage of Accuglim MP 1mg
The dosage of Accuglim MP 1mg Tablet is individualized based on your medical condition, response to treatment, and guidance from your healthcare provider. Typically, it is taken once daily with meals to minimize gastrointestinal side effects and reduce the risk of hypoglycemia.
The tablet should be swallowed whole with water, without crushing or chewing. Your doctor may adjust the dose over time to achieve optimal blood sugar control, so it’s essential to follow their instructions closely and not alter the dosage without consultation.
Other Dosages of Accuglim MP 1mg
How to Manage Side Effects?
- Consult Your Doctor
- Take as Prescribed
- Take with Meals
- Monitor Blood Sugar Levels
- Stay Hydrated
- Avoid Alcohol
- Inform Your Doctor of Other Medications
Warnings & Precautions
Risk of Hypoglycemia:
- May cause low blood sugar, especially if taken with other anti-diabetic drugs, missed meals, or excessive exercise.
1. Liver and Kidney Function:
- Use with caution in patients with liver or kidney impairment. Regular monitoring is advised.
2. Heart Conditions:
- Pioglitazone may increase the risk of heart failure. Not recommended in patients with a history of heart problems.
3. Avoid Alcohol Consumption:
- Alcohol can increase the risk of lactic acidosis and hypoglycemia when combined with metformin.
4. Lactic Acidosis Warning:
- Rare but serious condition linked to metformin. Watch for symptoms like muscle pain, shortness of breath, and extreme fatigue.
5. Weight Gain and Fluid Retention:
- Pioglitazone may cause weight gain and swelling. Report rapid weight gain or edema.
6. Bladder Cancer Risk:
- Long-term use of pioglitazone has been associated with a slightly increased risk of bladder cancer.
7. Not for Type 1 Diabetes or DKA:
- This medication is not suitable for treating type 1 diabetes or diabetic ketoacidosis.
8. Pregnancy and Breastfeeding:
- Use only if clearly needed and prescribed. Inform your doctor if you are pregnant or planning to conceive.
9. Regular Monitoring Needed:
- Routine blood tests to monitor blood sugar, kidney, and liver function are essential during treatment.
Storage
- Store below 25°C (77°F) in a cool, dry place.
- Keep away from moisture and direct sunlight.
- Do not freeze the medication.
- Store in original packaging to protect from air and humidity.
- Keep out of reach of children and pets.
- Do not use expired tablets—check expiry date before use.
- Dispose properly if the medicine is outdated or no longer needed—follow local guidelines or ask your pharmacist.
Frequently Asked Questions
1. What is Accuglim MP 1mg Tablets used for?
Ans. Accuglim MP 1mg Tablets is an antidiabetic medicine used to treat Type II diabetes mellitus when diet, exercise and treatment with single agents does not result in adequate response.
2. How and when to take Accuglim MP 1mg Tablets?
Ans. Take Accuglim MP 1mg Tablets preferably after meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight and disease condition.
3. How long should I take Accuglim MP 1mg Tablets?
Ans. You need to take Accuglim MP 1mg Tablets as long as your doctor or physician prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition
4. What is the best time to take Accuglim MP 1mg Tablets?
Ans. Accuglim MP 1mg Tablets must be taken with meals to avoid gastrointestinal side effects.
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