Acmeglim M2 Tablet

Introduction to Acmeglim M2 Tablet

Acmeglim M2 is an oral anti‑diabetic medication combining two active ingredients: glimepiride (2 mg) and metformin (500 mg). Glimepiride, a sulfonylurea, stimulates the pancreas to secrete more insulin, while metformin, a biguanide, reduces glucose production in the liver and improves insulin sensitivity.

By combining these mechanisms, Acmeglim M2 effectively lowers blood sugar levels and enhances glycemic control . Usually taken once daily with meals, its dosing is personalized by the doctor based on blood sugar response, and patients are encouraged to maintain regular diet and exercise habits.

It is manufactured by Acmedix Pharma. The company was officially incorporated on May 3, 2018, under the Registrar of Companies in Ahmedabad. The trio of designated partners—Dashrathbhai Kalidas Patel, Dilip Shankarbhai Chaudhary, and Javal Vishnukumar Patel—serve as the company’s directors/founding members since incorporation.

Uses of Acmeglim M2

Here are some primary uses of Acmeglim M2 Tablets:

• Treat Type II Diabetes Mellitus
• Prevention of Diabetes-Related Complications
• Improved Insulin Sensitivity and Pancreatic Function

How Does Acmeglim M2 Works?

Acmeglim M2 effectively reduces elevated blood glucose levels, where glimepiride acts by making the pancreas secrete more insulin to digest the circulating glucose and metformin acts by blocking the production of glucose by the liver. They collectively decrease the elevated blood glucose levels and makes the body respond better to insulin.

Side Effects of Acmeglim M2

Common Side Effects

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Loss of appetite
• Metallic taste in the mouth

Serious Side Effects

• Lactic Acidosis
• Severe Hypoglycemia
• Allergic Reactions
• Blood Disorders

Dosage of Acmeglim M2

The dosage of Acmeglim M2 is usually determined by a doctor based on the patient’s blood sugar levels, medical history, and response to treatment. Typically, it is taken once daily with breakfast or the first main meal to reduce the risk of hypoglycemia and stomach upset. Patients are advised to swallow the tablet whole with water, without crushing or chewing it.

The initial dose may be adjusted gradually to achieve optimal glycemic control while minimizing side effects. It’s essential not to skip doses or take more than prescribed. Regular monitoring of blood glucose and routine follow-ups with the doctor are important to ensure the effectiveness and safety of the treatment.

Other Dosages of Acmeglim M2

• Acmeglim M1 Forte
• Acmeglim M1
• Acmeglim M2 Forte
• Acmeglim MV 2
• Acmeglim MV 1

How to Manage Side Effects? 

• Communicate with Healthcare Provider
• Adhere to Dosage Instructions
• Do Not Discontinue Abruptly
• Stay Hydrated
• Take with Food (if recommended)
• Manage Nausea and Vomiting
• Use Sunscreen
• Monitor Blood Sugar Levels

Warnings & Precautions

1. Kidney and Liver Conditions:

• Use with caution in patients with kidney or liver impairment, as metformin can accumulate and increase the risk of lactic acidosis, a rare but life-threatening condition.

2. Regular Monitoring Required:

• Frequent blood glucose, kidney function, and liver tests are important to ensure the medication is working safely and effectively.

3. Not for Type 1 Diabetes or DKA:

• Acmeglim M2 is not suitable for type 1 diabetes or diabetic ketoacidosis (DKA), as it won’t be effective in insulin-dependent conditions.

4. Avoid Alcohol:

• Alcohol increases the risk of both lactic acidosis and hypoglycemia, and should be avoided during treatment.

5. During Illness or Surgery:

• In cases of serious infection, dehydration, fever, or upcoming surgery, your doctor may advise stopping the tablet temporarily to avoid complications.

6. Pregnancy and Breastfeeding:

• This medication is generally not recommended during pregnancy or while breastfeeding unless clearly advised by a healthcare provider.

7. Elderly Patients:

• Older adults are more sensitive to the side effects, particularly lactic acidosis and kidney function decline, so dose adjustments and monitoring may be needed.

Storage

• Store at room temperature between 15°C to 30°C (59°F to 86°F).
• Keep away from moisture and direct sunlight to preserve the tablet’s effectiveness.
• Do not refrigerate the medicine unless specifically instructed by a pharmacist.
• Keep the medication in its original packaging until use to avoid contamination.
• Store out of reach of children and pets to prevent accidental ingestion.
• Do not use expired tablets—always check the expiry date before use.
• Do not flush unused tablets down the toilet; dispose of them properly through local drug disposal programs.

Frequently Asked Questions

1. Can I consume alcohol while taking Acmeglim M2?

Ans. No. Do not consume alcohol while taking Acmeglim M2 as it can increase your blood sugar levels further.

2. Can Acmeglim M2 cause vitamin B12 deficiency?

Ans. Yes. The use of Acmeglim M2 can cause alternation in blood count. It can cause decrease in number of red blood cells making your skin look pallor and can make you feel tired and weak. Consult your doctor if you experience any of these symptoms.

3. What should I do if I miss a dose of Acmeglim M2?

Ans. If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Do not double the dose to make up for a missed one.

4. Can I stop taking Acmeglim M2 once my symptoms are relieved?

Ans. No, do not stop taking Acmeglim M2 without consulting your doctor. Continue to take Acmeglim M2 as instructed by your doctor to obtain better results.