About Extra Super Tadarise
Extra Super Tadarise is marketed as a combination tablet containing tadalafil 40 mg and dapoxetine hydrochloride 60 mg. These ingredients belong to different medicine classes and have different pharmacological actions.
Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor that supports erectile function by increasing blood flow to the penis in response to sexual stimulation. Dapoxetine is a short-acting selective serotonin reuptake inhibitor (SSRI) that has been used for premature ejaculation in certain countries.
Although the product is marketed for erectile dysfunction (ED) and premature ejaculation (PE), the presence of both ingredients does not establish that the combination is suitable or safe for routine use. The stated tadalafil strength is above the usual maximum recommended as-needed dose for ED in US prescribing information. In addition, dapoxetine product information warns against combining it with PDE5 inhibitors because of the potential for orthostatic hypotension.
The exact formulation, regulatory status and prescribing information should be verified by a qualified healthcare professional before this product is considered. It should not be self-administered.
Available Dosage
The product information supplied for Extra Super Tadarise lists a fixed-strength combination of tadalafil 40 mg and dapoxetine 60 mg per tablet.
Tadalafil and dapoxetine have different dosing recommendations when prescribed individually. The usual as-needed tadalafil dose for erectile dysfunction starts at 10 mg and may be adjusted to 5 mg or 20 mg according to individual response and tolerability. The 40 mg strength stated for this product is not a standard as-needed ED dose.
Dapoxetine treatment also requires individual assessment. Its suitability depends on medical history, other medicines, contraindications and the approved product information in the relevant country.
Do not interpret the product’s fixed strength or the dosage of another Tadarise formulation as a recommended dose. A healthcare professional must verify the exact product and assess its safety before use.
Strength
According to the product information, each Extra Super Tadarise tablet contains:
- Tadalafil 40 mg: A PDE5 inhibitor associated with the treatment of erectile dysfunction.
- Dapoxetine hydrochloride 60 mg: A short-acting SSRI used for premature ejaculation in certain countries.
These ingredients act through different mechanisms. However, a higher strength does not necessarily mean better effectiveness or greater suitability. The stated 40 mg tadalafil strength exceeds the usual maximum recommended as-needed dose for ED in US prescribing information.
The combination also raises an important interaction concern: dapoxetine product information advises against concomitant use with PDE5 inhibitors. Therefore, this formulation should not be presented as an established or routinely suitable dual-action treatment.
Extra Super Tadarise Other Strengths and Substitutes
- Tadarise 2.5
- Tadarise 5
- Tadarise 10
- Tadarise 20
- Tadarise 40
- Tadarise 60
- Tadarise Black 80
- Tadarise Pro 20
- Tadarise Pro 40
- Top Tadarise 50
- Tadarise Effervescent 20
- Tadarise 20 mg Oral Jelly
- Super Tadarise
How Does It Work?
Tadalafil and dapoxetine have different pharmacological actions.
Tadalafil
Tadalafil inhibits the phosphodiesterase type 5 (PDE5) enzyme. This helps preserve cyclic guanosine monophosphate (cGMP) activity in penile tissue, supporting smooth-muscle relaxation and increased blood flow during sexual stimulation.
It does not automatically produce an erection and does not directly increase sexual desire.
Dapoxetine
Dapoxetine is a short-acting selective serotonin reuptake inhibitor (SSRI). It affects serotonin signalling involved in ejaculation and may help delay ejaculation in appropriately selected men where its use is approved.
However, dapoxetine can interact with other medicines, including PDE5 inhibitors. Its combination with tadalafil should not be assumed safe. The applicable prescribing information and the potential for blood-pressure changes and fainting must be assessed by a healthcare professional.
Benefits of Extra Super Tadarise
The product is marketed as containing two ingredients associated with different sexual-health conditions. However, this does not establish that the fixed-dose combination provides a proven or safe dual benefit.
Tadalafil and dapoxetine should be assessed individually according to their approved indications, strengths, contraindications and potential interactions. The stated formulation should not be promoted as a guaranteed way to improve erection quality, ejaculation control, sexual stamina or satisfaction.
Possible Side Effects
The ingredients have different potential adverse effects.
Effects associated with tadalafil
- Headache
- Indigestion
- Facial flushing
- Nasal congestion
- Back pain
- Muscle pain
- Dizziness
Effects associated with dapoxetine
- Nausea
- Headache
- Dizziness
- Diarrhoea
- Insomnia
- Dry mouth
- Fainting or loss of consciousness
The likelihood and severity of adverse effects vary between individuals. The safety profile of the exact fixed-dose combination should not be assumed to be the same as that of either ingredient taken separately.
Seek urgent medical attention for chest pain, collapse or fainting, sudden vision or hearing loss, a severe allergic reaction, symptoms suggestive of serotonin syndrome, or an erection lasting four hours or longer.
Warning & Precautions
- PDE5 inhibitor interaction: Dapoxetine product information advises against concomitant use with PDE5 inhibitors such as tadalafil. The combination may increase the risk of orthostatic hypotension, dizziness and fainting.
- Nitrate medicines: Tadalafil must not be combined with nitrates such as nitroglycerin or isosorbide because the combination can cause a dangerous fall in blood pressure.
- Heart and blood-pressure conditions: People with significant cardiovascular disease, uncontrolled blood pressure, a recent heart attack or stroke, or conditions that make sexual activity inadvisable require medical assessment.
- Antidepressants and serotonergic medicines: Dapoxetine may interact with SSRIs, SNRIs, tricyclic antidepressants, MAO inhibitors and other medicines that affect serotonin. These combinations can increase the risk of serious adverse reactions, including serotonin syndrome.
- Alcohol: Alcohol may increase dizziness, impaired alertness and fainting risk with dapoxetine. Avoid alcohol when using dapoxetine-containing medicines.
- Liver and kidney conditions: People with impaired liver or kidney function need medical assessment because these conditions can affect medicine suitability and exposure.
- Seizure disorders and mental-health conditions: A history of seizures, depression, bipolar disorder or other significant psychiatric conditions should be discussed with a healthcare professional before considering dapoxetine.
- Driving and machinery: Dizziness, fainting or impaired alertness may make driving and operating machinery unsafe.
Safety Advice
The stated tadalafil 40 mg and dapoxetine 60 mg combination should not be self-administered or treated as a routine dosing option for erectile dysfunction and premature ejaculation.
Do not use the product based on the dosage instructions for another tadalafil or dapoxetine medicine. Do not combine it with other erectile dysfunction medicines, nitrates, or serotonergic medicines without a qualified healthcare professional’s review.
Before considering this formulation, verify the active ingredients, strengths, manufacturer information and regulatory status for the exact product. A healthcare professional should assess its potential interactions, contraindications and suitability.
Keep medicines in their original packaging, follow the storage instructions on the product label, and keep them out of reach of children.
Conclusion
Extra Super Tadarise is marketed as a combination of tadalafil 40 mg and dapoxetine 60 mg. Although the ingredients have different pharmacological actions associated with erectile dysfunction and premature ejaculation, the stated formulation raises important dosage and drug-interaction concerns.
The tadalafil strength is above the usual maximum recommended as-needed dose for erectile dysfunction in US prescribing information, and dapoxetine product information advises against combining it with PDE5 inhibitors. The product should therefore not be presented as a proven, routinely safe dual-action treatment. Its formulation and regulatory status require verification, and patients should seek qualified medical advice rather than self-medicate.









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