Hepbest 25mg Tenofovir Alafenamide Tablets

Introduction to Hepbest 25 mg Tablets

Hepbest 25mg Tablet is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. It prevents the multiplication of viruses in human cells. This stops the virus from producing new viruses and clears up your infection.

Hepbest Tablet should be used in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Take it with food, as this increases the absorption of the medicine into the body.

TAF is typically administered as a once-daily oral tablet, and its use should be under the supervision of a healthcare provider due to potential side effects and the need for regular monitoring of liver function.

It’s important to note that abrupt discontinuation of TAF in patients with HBV can lead to acute hepatitis exacerbation, so any changes in treatment should be managed by a healthcare professional.

Uses of Hepbest 25mg

Hepbest 25mg Tablet (Tenofovir Alafenamide) is primarily used for the following:

• Treatment of Chronic Hepatitis B (HBV)
• Part of HIV Treatment Regimen

How Does Hepbest 25 Works?

Hepbest 25mg (Tenofovir Alafenamide) works by inhibiting the replication of the hepatitis B virus (HBV) and HIV-1 in the body. It is a prodrug of tenofovir, which means it gets converted into the active form inside the liver cells.

Once activated, tenofovir blocks the viral enzyme reverse transcriptase, preventing the virus from multiplying and spreading. This helps reduce the viral load, improve liver function in people with chronic HBV, and control HIV infection when used in combination with other antiretroviral medications.

Side Effects of Hepbest

• Headache
• Diarrhea
• Vomiting
• Nausea
• Dizziness
• Rash
• Fatigue
• Weakness

Dosage of Hepbest 25 mg

The usual dosage of Hepbest 25mg (Tenofovir Alafenamide) is one tablet taken once daily with or without food. It is important to follow your healthcare provider’s instructions carefully, as the dose may vary depending on your specific condition (chronic hepatitis B or HIV-1) and any other medical factors.

Regular monitoring of kidney function and liver enzymes is recommended during treatment. Never stop or adjust the dose without consulting your doctor to avoid complications.

How to Manage Side Effects?

• Read the Patient Information Leaflet
• Communicate with Healthcare Provider
• Follow the Prescribed Dosage
• Take Medication with Food
• Stay Hydrated
• Avoid Alcohol and Certain Foods
• Monitor Blood Work

Warnings & Precautions

Here are the warnings and precautions for Hepbest 25mg (Tenofovir Alafenamide):

1. Kidney Problems

• Hepbest can cause kidney damage, especially in individuals with pre-existing kidney conditions. Regular monitoring of kidney function (such as serum creatinine levels) is essential during treatment.

2. Liver Disease

• Abrupt discontinuation of Hepbest in patients with chronic hepatitis B can lead to severe liver problems, including hepatic flare-ups. It’s crucial to consult your healthcare provider before stopping or changing your treatment.

3. Bone Health

• Long-term use of Hepbest may lead to bone density loss and increase the risk of fractures. Bone mineral density should be monitored, especially in those with risk factors for osteoporosis.

4. Lactic Acidosis

• Lactic acidosis, a rare but serious condition, can occur, causing symptoms like weakness, muscle pain, and breathing difficulty. Immediate medical attention is needed if these symptoms develop.

5. HIV Resistance

• Hepbest should only be used for HIV-1 infection in combination with other antiretroviral medications. Monotherapy can lead to drug resistance and treatment failure.

6. Pregnancy and Breastfeeding

• Hepbest should be used during pregnancy only if clearly needed. It is not known if the drug passes into breast milk, so consult your doctor before breastfeeding.

Storage

• Store at room temperature
• Avoid extreme temperatures
• Keep in the original packaging
• Keep away from children and pets
• Check expiration date

Frequently Asked Questions

1. Does Hepbest 25mg Tablets prevent passing of HIV-1 and HBV to others?

In case of HIV-1 infection, Hepbest Tablet may reduce the risk of passing the virus to others, but the chances of infecting others still persist. However, in case of HBV infection, Hepbest Tablet has not proven to reduce risk of transferring the virus to others. Therefore, the patients of both HIV-1 infection and HBV infection should practice safe sex and should not share dirty needles.

2. Is Hepbest 25mg Tablets safe?

Hepbest 25mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor’s instructions carefully and let your doctor know if any of the side effects bother you.

3. How should I take Hepbest 25mg Tablets?

You should take Hepbest 25mg Tablet in the dose and duration advised by your doctor. Hepbest 25mg Tablet works best when taken with meals or just afterwards. However, taking it without food does not reduce its effectiveness. If you have any doubts, consult your doctor.

4. How long do I need to take Hepbest 25 Tablets for HBV infection?

Duration of treatment will depend on the severity of HBV infection. You will need to take periodic blood tests to keep a check on the viral load and number of T cells. Your doctor will then decide the duration of the medicine accordingly. In some cases, treatment is required life long.