Hertraz 440mg Injection

Introduction to Hertraz 440 mg Injection

Hertraz 440mg Injection is a medication used in the treatment of certain types of cancer, primarily HER2-positive breast cancer and gastric cancer. The active ingredient in Hertraz is trastuzumab, a monoclonal antibody that targets the HER2 (human epidermal growth factor receptor 2) protein. HER2 is a protein that promotes the growth of cancer cells, and its overexpression is associated with aggressive forms of cancer. By binding to this protein, trastuzumab helps to inhibit the growth and proliferation of cancer cells that overexpress HER2.

The injection is administered intravenously, typically every 3 weeks, though the exact schedule can vary depending on the specific cancer being treated and the individual’s response to the medication. Hertraz is often used in combination with other cancer therapies, such as chemotherapy or hormone therapy, to enhance its effectiveness. The dosage of 440mg is specifically designed to be effective for treating these cancers while minimizing the risk of side effects.

As a targeted therapy, Hertraz has a mechanism of action that is more specific to HER2-positive cancer cells, potentially reducing the risk of damage to normal cells compared to traditional chemotherapy. However, despite its targeted approach, Hertraz can still cause side effects. Common side effects may include fever, chills, nausea, and infusion-related reactions. More serious side effects can include heart problems, such as decreased heart function or heart failure, which necessitates regular monitoring by a healthcare professional.

The administration of Hertraz requires careful consideration of the patient’s overall health and other medications they may be taking. Prior to starting treatment, patients typically undergo various tests to ensure that Hertraz is suitable for them and to monitor for any potential interactions or contraindications. Regular follow-up appointments are also necessary to assess the effectiveness of the treatment and to manage any side effects.

Uses of Hertraz 440 mg 

Hertraz 440mg Injection, containing trastuzumab, is used primarily for the treatment of cancers that are characterized by the overexpression of the HER2 protein. Its main uses include:

• HER2-Positive Breast Cancer
• HER2-Positive Gastric Cancer
• Early-Stage HER2-Positive Breast Cancer
• Adjuvant Therapy
• Neoadjuvant Therapy

In all these uses, Hertraz is administered under the guidance of a healthcare professional, and its effectiveness is monitored through regular assessments and evaluations. The decision to use Hertraz depends on the specific characteristics of the cancer and the individual patient’s overall health and treatment goals.

How Does Hertraz 440 Works? 

Hertraz 440mg Injection is a monoclonal antibody. It works by blocking the actions of certain cellular proteins (HER2) that triggers cancer cell formation. It also blocks various downstream cell signalling pathways that triggers cancer growth within the body. As a result, it reduces cancer formation and prevents its further growth within the body.

Side Effects of Hertraz 440

Common Side Effects 

• Infusion-Related Reactions
• Nausea and Vomiting
• Fatigue
• Diarrhea
• Rashes
• Heart Issues
• Low Blood Cell Counts
• Infection Risk

Serious Side Effects.

• Heart Problems
• Severe Infusion Reactions
• Pulmonary Issues
• Serious Infections
• Hepatic (Liver) Issues
• Severe Blood Cell Count Abnormalities

Rare Side Effects

• Severe Allergic Reactions
• Severe Liver Toxicity
• Severe Skin Reactions
• Neurological Issues
• Severe Gastrointestinal Issues
• Unusual Bleeding or Bruising

Dosage of Hertraz 440 mg

Hertraz 440 mg Injection contains an active ingredient, Trastuzumab, which is used in the treatment of breast cancer and stomach cancer. This medicine is available in various strengths and substitutes & must be given on doctor’s prescription only. You should consult your doctor for dosage and time because age and severity of the disease differ from person to person and it can only be judged by your doctor.

Adults are advised to take Hertraz 440 mg Injection at a fixed time with or without food as instructed by your Doctor. You must take this medicine regularly on time for better results.

Other Dosages of Hertraz 440mg

• Hertraz 150mg

How to Manage Side Effects?

• Consult with Healthcare Professional
• Follow Dosage Instructions
• Pre-medication for Infusion Reactions
• Monitor for Allergic Reactions
• Managing Infusion-Related Reactions

Warning & Precautions

• Allergy
• Liver/kidney disease
• You must undergo biopsy test during Trastuzumab treatment to check the effect of Trastuzumab
• It is recommended to test the over expression of human epidermal growth factor receptor (HER2) before the administration of this medicine is initiated
• Regular monitoring of blood cell components is recommended while this medicine is being administered
• You should not drive or operate machinery while taking this medicine as it may cause dizziness
• You must always consult your doctor immediately to get the best possible treatment when you are suffering from any of the above-mentioned conditions.

Safety Advice

• Administered by Healthcare Professionals
• Medical History Disclosure
• Monitoring During Infusion
• Pregnancy and Breastfeeding
• Cardiac Function Monitoring
• Avoid Live Vaccines
• Interactions with Other Medications
• Regular Follow-up
• Do Not Self-Administer
• Storage
• Report Adverse Events
• Compliance with Treatment Plan

Frequently Asked Questions

1. What are the serious side effects of Hertraz 440mg Injection?

Ans. There are various side effects related to Hertraz 440mg Injection such as sore throat, fever, chills, excessive tiredness, pale skin, nosebleeds, and other unusual bruising or bleeding. One can also experience stomach pain, seizures, hallucinations, muscle cramps, and spasms. Along with that, nausea or vomiting, loss of appetite, fatigue, rapid heart beat, discoloration of urine; decreased amount of urine, difficulty in urinating, pain when urinating, and other signs of infection can also be observed with the use of Hertraz 440mg Injection. You should call your doctor immediately if you notice any such symptoms.

2. How long after Hertraz 440mg Injection therapy can I get pregnant?

Ans. Women of child-bearing age should use effective contraception during Hertraz 440mg Injection therapy and for 7 months after completing the treatment. You can plan your pregnancy after 7 months of treatment with Hertraz 440mg Injection.

3. How long should Hertraz 440mg Injection be taken?

Ans. Patients with early breast cancer should take Hertraz 440mg Injection for 1 year or until disease recurs, whichever occurs first. It is not advised to extend the treatment beyond 1 year in patients of early breast cancer.

4. Is fasting required before administering Hertraz 440mg Injection?

Ans. No, fasting is not required before administering Hertraz 440mg Injection. It should be given under the guidance of a doctor who is experienced in giving cancer chemotherapy and should be given only by a healthcare professional.