Bevazza 100mg/4ml Injection

Introduction to Bevazza 100mg/4ml Injection

Bevazza 100mg/4ml Injection is an Anticancer medication. It is used in the treatment of cancer of colon and rectum, non-small cell lung cancer, kidney cancer, brain tumor, ovarian and cervical cancer. It helps to prevent the growth of new blood vessels that feed tumors and stops tumors from growing. This medicine is manufactured by Lupin Ltd.

This medication is typically administered intravenously by a healthcare professional in a clinical setting. The dosage and frequency of administration depend on the specific type of cancer being treated, the patient’s overall health, and their response to the treatment. Bevazza 100mg/4ml Injection is often used in combination with other chemotherapeutic agents to enhance its efficacy.

Uses of Bevazza 100mg/4ml

Bevazza 100mg/4ml Injection, containing the active ingredient bevacizumab, is primarily utilized in the treatment of several types of cancer. The main uses of this medication include:

• Colorectal Cancer
• Non-Small Cell Lung Cancer (NSCLC)
• Kidney Cancer
• Glioblastoma
• Ovarian Cancer
• Cervical Cancer

How Does Bevazza 100mg/4ml Works?

Bevazza 100mg/4ml is an anticancer medication containing bevacizumab, a monoclonal antibody that targets vascular endothelial growth factor A (VEGF-A). VEGF-A is a protein that promotes the formation of new blood vessels (angiogenesis), a process that tumors exploit to secure a blood supply for their growth and survival.

By binding to VEGF-A, bevacizumab prevents it from interacting with its receptors on endothelial cells, thereby inhibiting the development of new blood vessels within tumors. This inhibition of angiogenesis effectively starves the tumor of the nutrients and oxygen it requires, slowing its growth and potentially reducing its size.

Additionally, by normalizing the tumor vasculature, bevacizumab can enhance the delivery of chemotherapeutic agents to the tumor site, improving the efficacy of combination therapies.

Side Effects of Bevazza 100mg/4ml

Common Side Effects

• Fatigue
• Nausea and vomiting
• Mild bleeding
• Skin rash
• Mucositis
• Protein in the urine

Serious Side Effects

• Severe bleeding
• High blood pressure crisis
• Blood clots
• Slow or impaired wound healing
• Kidney problems

Dosage of  Bevazza 100mg/4ml

Bevazza 100 mg Injection contains an active ingredient, Bevacizumab, which is used in the treatment of Cancer of colon & rectum, Non-small cell lung cancer, Brain tumor, Kidney cancer, Ovarian Cancer, Glioblastoma Multiforme, Cervical cancer, Peritoneal Cancer, Fallopian Tube Cancer.

This medicine is obtainable in different substitutes & strengths & has got to be purchased or taken on doctor’s prescription only. You must talk about with your physician for adjustment of dosage & time of the medicine since age & severity of the disease differ from person to person, and this can only be finest judged by your doctor.

How to Manage Side Effects?

• Stay Hydrated
• Monitor Blood Pressure
• Watch for Signs of Bleeding
• Manage Fatigue
• Stay in Regular Contact with Your Oncologist
• Take with Food
• Do Rest
• Follow-up Appointments

Warnings & Precautions

Here are the warnings and precautions associated with Bevazza (Bevacizumab) 100mg/4ml:

1. Hypertension Risk:

• Bevacizumab may cause or worsen high blood pressure; regular monitoring is essential.

2. Delayed Wound Healing:

• Avoid surgery while on this medication and for several weeks after stopping it.

3. Gastrointestinal Perforation:

• Rare but serious; symptoms like severe abdominal pain should be reported immediately.

4. Increased Risk of Infections:

• Bevacizumab may suppress immune function, so monitor for signs like fever or persistent cough.

5. Protein in Urine (Proteinuria):

• Regular urine tests may be required, as it can lead to kidney issues.

6. Thromboembolic Events:

• Risk of blood clots, heart attack, or stroke may be elevated.

7. Pregnancy and Breastfeeding:

• Not recommended during pregnancy; effective contraception is advised during treatment and for at least 6 months after the last dose.

8. Allergic Reactions:

• Can cause serious infusion-related reactions; patients are usually monitored closely during administration.

9. Use in the Elderly:

• Caution is advised due to a higher risk of side effects such as thromboembolism or bleeding.

Safety Advice

• Monitor blood pressure regularly to avoid serious complications.
• Avoid surgery during and shortly after treatment period.
• Report any unusual bleeding or bruising immediately to doctor.
• Use effective contraception during and after treatment course.
• Stay hydrated and maintain a healthy, balanced diet.
• Notify doctor if experiencing chest pain or shortness breath.
• Attend all scheduled follow-up tests and medical appointments.

Frequently Asked Questions

1. What kinds of cancer can Bevazza Injection be used for ?

Ans. Bevazza Injection is approved for the treatment of cancer of the colon or rectum that has spread to other parts of the body. It must be given along with chemotherapy. Other types of cancers that it helps with includes certain types of lung cancer, kidney cancer, ovarian cancer, cervical cancer, and glioblastoma (a type of brain tumor).

2. How is Bevazza Injection given?

Ans. Bevazza Injection is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. Your doctor will decide your dose and duration and will monitor you for signs of an infusion reaction.

3. How long can I take Bevazza Injection for?

Ans. You keep taking Bevazza Injection as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking Bevazza Injection. If your cancer progresses during this initial treatment, talk to your doctor if a different chemotherapy may be an option.

4. How Bevazza Injection works differently from chemotherapy?

Ans. Chemotherapy attacks fast-growing cells, like cancer cells. In contrast, the purpose of Bevazza Injection is to prevent the growth of new blood vessels that feed tumors. This causes the Tumour to shrink, or to stop growing.