Intaxel 100mg Injection

Introduction to Intaxel 100 mg Injection

Intaxel 100mg Injection contains Paclitaxel which belongs to a group of Anti-cancer medicines called Taxanes. Intaxel 100mg Injection is used to treat ovarian and breast cancer as a first line of therapy and as a second line of treatment when platinum containing medicines (such as cisplatin) or anthracyclines are insufficient to treat the disease in affected individuals.

Intaxel 100mg Injection is also used to treat advanced NSCLC (non-small cell lung cancer) when surgery/radiation therapy is not suitable. The medicine is also indicated for use to treat AIDS-related Kaposi’s sarcoma when other treatments (such as anthracyclines) are insufficient to treat the disease in affected individuals.

Intaxel 100mg Injection is not recommended for use in patients allergic to paclitaxel and polyoxyethylated castor oil. It is also not recommended for use in patients with few white blood cells count and serious & uncontrolled infection. The medicine is also not used in patients suffering from severe liver disease.

Before receiving Intaxel 100mg Injection , inform your doctor if you had previously received radiation to your chest and/or suffering from thrombocytopenia (low platelet count)/acute infections (such as herpes zoster, chickenpox, herpes), kidney problems (such as chronic kidney disease), liver problems (such as mild/moderate hepatic impairment) and/or heart problems (such as severe coronary artery disease, myocardial infarction and arrhythmias).

Intaxel 100mg Injection is not recommended for use during pregnancy. Women of child-bearing potential should use effective contraception method while receiving Intaxel 100mg Injection which should be continued for next-6 months after completing the treatment. The medicine is also not recommended for use in breastfeeding women.

Intaxel 100mg Injection is also not recommended for use in children and adolescents (aged below 18 years). The medicine can be used with caution in elderly patients (aged above 65 years) after consulting the doctor.

The most common side effects of receiving Intaxel 100mg Injection are minor allergic reactions (such as flushing, rash, itching), shortness of breath, sore throat/mouth ulcers, diarrhea, nausea, vomiting and/or loss of hair. Consult your doctor if any of these symptoms worsen.

Uses of Intaxel 100 mg 

• Treats ovarian and breast cancer.
• Treats advanced NSCLC (non-small cell lung cancer)
• Treats AIDS-related Kaposi’s sarcoma in affected individuals.

How Does Intaxel 100 mg Injection Works

Intaxel 100mg Injection works by interfering with the microtubule structures in the cell (substance which aids cancer cells to divide and multiply) thus inhibiting the growth of cancer cells and preventing its spread in affected individuals.

Side Effects of Intaxel 100

• Minor allergic reactions such as flushing, rash and/or itching
• Infections such as upper respiratory infection, urinary tract infection
• Shortness of breath
• Sore throat/mouth ulcers, sore and red mouth
• Diarrhea, nausea, vomiting
• Loss of hair
• Pain in the muscles, cramps, joints
• Fever, severe chills, headache, dizziness, tiredness, looking pale
• Bleeding, bruising more easily than normal

Common Side Effects

• Minor allergic reactions such as flushing, rash and/or itching
• Infections such as upper respiratory infection, urinary tract infection
• Shortness of breath
• Sore throat/mouth ulcers, sore and red mouth
• Diarrhea, nausea, vomiting
• Loss of hair
• Pain in the muscles, cramps, joints
• Fever, severe chills, headache, dizziness, tiredness, looking pale
• Bleeding, bruising more easily than normal

 Rare Side Effects

• Febrile neutropenia (type of fever) due to low white blood cell count associated with fever and increased risk of infection
• Motor neuropathy (disease that affects your body’s motor nerves)
• Pulmonary embolism (blockade of lung artery), lung fibrosis (damaged/scarred lung tissue), interstitial pneumonia (scarring of lung tissue), pleural effusion (build of fluid between lungs and chest)
• Bowel obstruction, bowel perforation, inflammation of colon, inflammation of the pancreas (pancreatitis)
• Skin redness
• Peritonitis (inflammation of abdominal layer)
• Fever, dehydration, weakness

Dosage of Intaxel 100 mg

Intaxel 100 mg/ 16.67 ml Injection contains an active ingredient, Paclitaxel, which is used in the treatment of breast cancer, non-small cell lung cancer and pancreatic cancer. This medicine is available in various strengths and substitutes & must be given on doctor’s prescription only. You should consult your doctor for dosage and time because age and severity of the disease differ from person to person and it can only be judged by your doctor.

Adults are advised to take Intaxel 100 mg/ 16.67 ml Injection at a fixed time with or without food as instructed by your Doctor. You must take this medicine regularly on time for better results

How to Manage Side Effects

• Consult with Healthcare Provider
• Allergic Reactions
• Nausea and Vomiting
• Hair Loss
• Fatigue
• Peripheral Neuropathy
• Muscle and Joint Pain

Warning & Precautions

• Allergy
• Liver/kidney disease
• You must use two methods of contraception while on this therapy & 3 months after it to avoid pregnancy
• You must get your regular blood tests done to monitor your blood cells and liver function during treatment with this medicine
• You should not drive or operate machinery while taking this medicine as it may cause dizziness
• You must always consult your doctor immediately to get best possible treatment when you are suffering from any of the above mentioned conditions.

Safety Advice

• Medical Supervision: Intaxel 100 should be administered by a qualified healthcare professional in a hospital or clinical setting. Do not attempt to self-administer this medication.
• Allergic Reactions: Inform your doctor about any known allergies or hypersensitivity to paclitaxel or other medications. If you experience signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, seek immediate medical attention.
• Pregnancy and Breastfeeding: Intaxel 100 may cause harm to the fetus and is generally not recommended during pregnancy. If you are pregnant or planning to become pregnant, discuss the risks and benefits with your doctor. Avoid breastfeeding while on this medication.
• Blood Cell Counts: Regularly monitor your blood cell counts during treatment. Paclitaxel can cause a decrease in blood cell production, leading to an increased risk of infections, anemia, and bleeding.

Frequently Asked Questions

1. What is Intaxel 100mg Injection used for?

Ans. Intaxel 100mg Injection is used to treat ovarian and breast cancer as a first line of therapy and as a second line of treatment when platinum containing medicines (such as cisplatin) or anthracyclines are insufficient to treat the disease. It is also used to treat advanced NSCLC (non-small cell lung cancer) and AIDS-related Kaposi’s sarcoma in affected individuals.

2. How Intaxel 100mg Injection works?

Ans. Intaxel 100mg Injection works by interfering with the microtubule structures in the cell (substance which aids cancer cells to divide and multiply) thus inhibiting the growth of cancer cells and preventing its spread in affected individuals.

3. What are the most common side effects of receiving Intaxel 100mg Injection?

Ans. The most common side effects of receiving Intaxel 100mg Injection are minor allergic reactions (such as flushing, rash, itching), shortness of breath, sore throat/mouth ulcers, diarrhea, nausea, vomiting and/or loss of hair. Consult your doctor if any of these symptoms worsen.

4. How to administer Intaxel 100mg Injection?

Ans. Intaxel 100mg Injection will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.