Entavir 1mg Tablet

Introduction to Entavir 1mg Tablet

Entavir 1mg tablet, containing the active ingredient tenofovir disoproxil fumarate, is a medication primarily used for the treatment of chronic hepatitis B virus (HBV) infection. Hepatitis B is a serious viral infection that affects the liver, leading to inflammation, liver damage, and potentially life-threatening complications such as cirrhosis and liver cancer if left untreated.

Entavir 1mg Tablet is not a cure for HIV or AIDS and only helps to decrease the amount of HIV in your body. This helps to lower your risk of getting HIV-related complications and improves your lifespan. It is prescribed in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need.

The medication is typically prescribed as a long-term therapy, taken orally once daily. It is well-absorbed from the gastrointestinal tract and converted into its active form, tenofovir, in the body. Tenofovir competes with natural substrates to integrate into viral DNA, effectively disrupting the replication process and preventing the virus from spreading.

Uses of Entavir 1 mg

Entavir 1 mg (Tenofovir disoproxil fumarate) is primarily used for the treatment of chronic hepatitis B virus (HBV) infection. Here are the key uses of Entavir 1 mg:

• Treatment of Chronic Hepatitis B
• Reduction of Liver Inflammation
• Prevention of Liver Cirrhosis
• Decreased Risk of Liver Cancer
• Maintenance Therapy
• Adjuvant Therapy

How does Entavir 1 Works?

Entavir 1 Mg Tablet has an active ingredient; Entecavir is an antiviral medication which prevents the multiplication of virus in human cells. This stops the virus from producing new viruses & clears up your infection.

Entecavir drug is a nucleoside analog, or a Deoxyguanosine analogue that belongs to a class of carbocyclic nucleosides & inhibits reverse transcription, DNA replication & transcription in the viral replication process.

Other nucleoside and nucleotide analogues include telbivudine, lamivudine, Adefovir Dipivoxil, & tenofovir. Entecavir decreases the amount of HBV in the blood by reducing its ability to multiply & infect new cells.

Side Effects of Entavir

• Headache
• Nausea
• Rash
• Vomiting
• Fatigue
• Stomach pain
• Diarrhea

Dosage of Entavir 1mg

Entavir 1 Mg Tablet contains an active ingredient, Entecavir, which is used in the treatment of chronic hepatitis B virus (HBV) infection. This medicine is available in different substitutes & strengths & has got to be purchased or given on doctor’s prescription only.

You must consult your physician for adjustment of dosage & time of the medicine because age and severity of the disease differ from person to person and it can only be best judged by your doctor.

Adults are advised to take Entavir 1 Mg Tablet at a fixed time without food as instructed by your Doctor. You must take Entavir 1 Mg Tablet regularly on time for better results.

Other Dosages of Entavir 1mg

• Entavir 0.5mg

How to Manage Side Effects? 

• Communicate with Healthcare Provider
• Stick to Prescribed Dosage
• Take with Food
• Stay Hydrated
• Avoid Alcohol and Certain Foods
• Monitor Liver Function
• Report Serious Side Effects

Warnings & Precautions

Entehep 1mg (Entecavir) carries several important warnings and precautions, similar to those of Entecavir 0.5mg. Here are the key points:

1. Liver Disease:

• Entecavir should be used with caution in patients with liver conditions like cirrhosis. It may worsen liver disease, especially if treatment is stopped abruptly. Regular monitoring of liver function is recommended.

2. HIV Co-infection:

• Entecavir is not effective against HIV and may not be suitable for individuals co-infected with both hepatitis B and HIV. It’s important to manage both infections carefully to avoid resistance development.

3. Discontinuation of Treatment:

• Stopping Entecavir suddenly can lead to a flare-up of hepatitis B, potentially causing severe liver damage. Do not stop the medication without consulting your healthcare provider.

4. Lactic Acidosis:

• Lactic acidosis (buildup of lactic acid in the blood) is a rare but serious side effect. Symptoms may include nausea, vomiting, unusual tiredness, and muscle pain. Immediate medical attention is required if any of these symptoms occur.

5. Kidney Function:

• Entecavir is primarily cleared through the kidneys, so it may accumulate in patients with kidney problems. Dose adjustments may be necessary in those with impaired renal function, and kidney function should be monitored regularly.

6. Pregnancy and Breastfeeding:

• Entecavir should only be used during pregnancy if the benefits outweigh the risks. Consult with a doctor before using Entecavir if you are pregnant or planning to become pregnant. It is not known whether Entecavir is excreted in breast milk, so it should be used with caution in breastfeeding mothers.

7. Resistance:

• Improper use of Entecavir may lead to resistance. Adhere to the prescribed dosage and treatment plan to reduce the risk of resistance.

8. Allergic Reactions:

• In rare cases, severe allergic reactions can occur, with symptoms like rash, itching, swelling, or difficulty breathing. Seek immediate medical attention if any of these symptoms develop.

Storage

• Store the medication at room temperature, typically between 20°C to 25°C (68°F to 77°F).
• Protect the tablets from direct light by keeping them in their original packaging or a dark, dry place.
• Store in a dry place, away from humidity, as moisture can affect the stability of the medication.
• Ensure the medication is stored securely, out of the reach of children to prevent accidental ingestion.
• Avoid storing Entecavir in the refrigerator, as cold temperatures may affect its effectiveness.
• Check the expiration date before use. Do not use the medication past its expiration date.

Frequently Asked Questions

1. How should Entavir 1mg Tablet be taken?

Ans. You should take Entavir 1mg Tablet exactly as prescribed by your doctor and continue taking it till your doctor tells you to stop. It is usually taken once a day on an empty stomach, at least 2 hours after a meal and at least 2 hours before the next meal. It is advised to take it around the same time every day. If not sure, consult your doctor.

2. Can Entavir 1mg Tablet cause liver problems?

Ans. Yes, Entavir 1mg Tablet can cause serious liver problems like hepatomegaly (enlargement of the liver) and steatosis (an increased build-up of fat in the liver). It is important to know that hepatomegaly along with steatosis is a serious medical emergency which requires immediate medical attention.

3. What are the symptoms of serious liver problems?

Ans. The symptoms of liver problems include jaundice (a condition in which your skin or the white part of your eyes turns yellow), dark-colored urine, light-colored stools, loss of appetite, nausea and stomach pain. These symptoms are more common in women, overweight patients, or if you have been on Entavir 1mg Tablet for a long time. Immediately contact your doctor if you experience any such symptoms.

4. What is drug resistance? Can I develop drug resistance with Entavir 1mg Tablet?

Ans. Drug resistance is a state where the medicine which was once effective in treating an infection becomes ineffective. This mainly happens due to the ability acquired by the virus or bacteria to get modified inside the body which affects the overall working of the medicine. Hence, the medicine is no longer able to fight against the virus or bacteria. Generally, drug resistance with Entavir 1mg Tablet is more likely to happen if you take less dose than what is recommended.