Paclitax 300mg Injection

Introduction to Paclitax 300mg Injection

Paclitax 300mg Injection contains Paclitaxel which belongs to a group of Anti-cancer medicines called Taxanes. Paclitax 300mg Injection is used to treat ovarian and breast cancer as a first line of therapy and as a second line of treatment when platinum containing medicines (such as cisplatin) or anthracyclines are insufficient to treat the disease in affected individuals.

Paclitax 300mg Injection is also used to treat advanced NSCLC (non-small cell lung cancer) when surgery/radiation therapy is not suitable. The medicine is also indicated for use to treat AIDS-related Kaposi’s sarcoma when other treatments (such as anthracyclines) are insufficient to treat the disease in affected individuals.

Paclitax 300mg Injection is not recommended for use in patients allergic to paclitaxel and polyoxyethylated castor oil. It is also not recommended for use in patients with few white blood cells count and serious & uncontrolled infection. The medicine is also not used in patients suffering from severe liver disease.

Before receiving Paclitax 300mg Injection, inform your doctor if you had previously received radiation to your chest and/or suffering from thrombocytopenia (low platelet count)/acute infections (such as herpes zoster, chickenpox, herpes), kidney problems (such as chronic kidney disease), liver problems (such as mild/moderate hepatic impairment) and/or heart problems (such as severe coronary artery disease, myocardial infarction and arrhythmias).

Paclitax 300mg Injection is not recommended for use during pregnancy. Women of child-bearing potential should use effective contraception method while receiving Paclitax 300mg Injection which should be continued for next-6 months after completing the treatment. The medicine is also not recommended for use in breastfeeding women.

Paclitax 300mg Injection is also not recommended for use in children and adolescents (aged below 18 years). The medicine can be used with caution in elderly patients (aged above 65 years) after consulting the doctor.

Uses of Paclitax 300 mg

• Treats ovarian and breast cancer.
• Treats advanced NSCLC (non-small cell lung cancer)
• Treats AIDS-related Kaposi’s sarcoma in affected individuals.

How Does Paclitax 300 Works

Paclitax 300mg Injection works by interfering with the microtubule structures in the cell (substance which aids cancer cells to divide and multiply) thus inhibiting the growth of cancer cells and preventing its spread in affected individuals.

Side Effects of Paclitax 300 

Common Side Effects

• Minor allergic reactions such as flushing, rash and/or itching
• Infections such as upper respiratory infection, urinary tract infection
• Shortness of breath
• Sore throat/mouth ulcers, sore and red mouth
• Diarrhea, nausea, vomiting
• Loss of hair
• Pain in the muscles, cramps, joints
• Fever, severe chills, headache, dizziness, tiredness, looking pale
• Bleeding, bruising more easily than normal
• Signs of peripheral neuropathy such as numbness, tingling/weakness in arms and legs
• Temporary mild nail change and skin changes
• Reactions at injection sites such as localized swelling, pain and/or redness of the skin.

 Rare Side Effects

• Febrile neutropenia (type of fever) due to low white blood cell count associated with fever and increased risk of infection
• Motor neuropathy (disease that affects your body’s motor nerves)
• Pulmonary embolism (blockade of lung artery), lung fibrosis (damaged/scarred lung tissue), interstitial pneumonia (scarring of lung tissue), pleural effusion (build of fluid between lungs and chest)
• Bowel obstruction, bowel perforation, inflammation of colon, inflammation of the pancreas (pancreatitis)
• Skin redness
• Peritonitis (inflammation of abdominal layer)
• Fever, dehydration, weakness
• Anaphylactic reactions (life threatening allergic reaction).

Dosage of Paclitax 300mg Injection

Paclitax 300 Mg Injection contains an active ingredient, Paclitaxel, which is used in the treatment of breast cancer, non-small cell lung cancer and pancreatic cancer. This medicine is available in various strengths and substitutes & must be given on doctor’s prescription only. You should consult your doctor for dosage and time because age and severity of the disease differ from person to person and it can only be judged by your doctor.

Adults are advised to take Paclitax 300 Mg Injection at a fixed time with or without food as instructed by your Doctor. You must take this medicine regularly on time for better results.

Other Dosages of Paclitax 300mg Injection

• Paclitax 30mg Injection
• Paclitax 100mg Injection

How to Manage Side Effects

• Communication with Healthcare Team
• Pre-medication
• Infusion Setting
• Infusion Monitoring
• Allergy Testing
• Nausea and Vomiting
• Fatigue Management
• Hair Loss
• Oral Care
• Diarrhea Management
• Peripheral Neuropathy

Warning & Precautions 

• Allergy
• Liver/kidney disease
• You must use two methods of contraception while on this therapy & 3 months after it to avoid pregnancy
• You must get your regular blood tests done to monitor your blood cells and liver function during treatment with this medicine
• You should not drive or operate machinery while taking this medicine as it may cause dizziness
• You must always consult your doctor immediately to get best possible treatment when you are suffering from any of the above mentioned conditions.

Safety Advice

• Medical Supervision
• Allergy Testing
• Infusion Setting
• Infusion Monitoring
• Pregnancy and Breastfeeding
• Blood Cell Counts
• Liver and Kidney Function
• Heart Health
• Peripheral Neuropathy
• Avoid Live Vaccines

Frequently Asked Questions

1. Is Paclitax 300mg Injection generic/ Taxane/ FDA approved/cytotoxic?

Ans. Yes, Paclitax 300mg Injection is generic/ Taxane/ FDA approved/ cytotoxic

2. Is Paclitax 300mg Injection a vesicant?

Ans. Paclitax 300mg Injection is usually a vesicant (irritant)

3. Is Paclitax 300mg Injection light sensitive/ hydrophobic/ cardiotoxic?

Ans. Yes, Paclitax 300mg Injection is light sensitive/ hydrophobic/ cardiotoxic

4. Does Paclitax 300mg Injection cause hair loss?

Ans. Yes, Paclitax 300mg Injection may cause hair loss as a side effect. Please inform your doctor about any side effect while you are on Paclitax 300mg Injection therapy.