Xolnic 4 mg Injection

Xolnic 4 mg Injection belongs to bisphosphonate class, containing an active ingredient, Zoledronic Acid, also known as Zoledronate. It is used to treat the porosity or weakening of the bones (Osteoporosis) caused mainly after menopause (postmenopausal Osteoporosis), also due to usage of steroids or other medicines, changes in hormone levels, inadequate diet intake, etc. It is manufactured by Khandelwal Laboratories Pvt. Ltd.

Apart from that, Xolnic Injection can reduce the risk of breakdown of bones during cancer. It is also used to treat raised levels of calcium in the blood in people who have cancer. This medicine is also used in the treatment of Paget’s disease in which disruption of the replacement of old bone cells with new bone cells occurs. Osteoporosis is a bone disease which occurs when the body loses too much bone (calcium) into the blood, makes too little bone, or both. As a result, bones become porous, weak, less and fragile, indicating that they may get broken easily from a minor fall or slightest trauma.

Also, in severe cases, people can get bone fractures even from sneezing or small bumps. Symptoms of Osteoporosis are not visible in the early stages. Still, when the disease progress and bones become weaker, one can observe the signs and symptoms like Back pain, which may be caused by a fractured vertebra, body pain, loss of height over time, stooped posture, frequent bone fractures even in slight injuries.

Uses of The Xolnic 4 mg

Xolnic 4 mg Injection is used for the treatment in the following conditions:

• Postmenopausal Osteoporosis (postmenopausal condition, in which bone become porous and fragile due to desorption of calcium from bone)
• Hypercalcemia (high levels of calcium in the blood due to desorption of bone)
• Paget’s disease (disruption of the replacement of old bone tissue with new bone tissue)

How Does Xolnic 4 mg Works?

Xolnic 4 mg Injection has an active ingredient, Zoledronic Acid, which is a bisphosphonate. This medicine acts by suppressing the activity of osteoclasts, the cells present in the bone itself and responsible for desorption of calcium from bones which destroy bone only. This injection, however, strengthens the bones & minimizes the risk of fractures.

Side Effects of  Xolnic 4 mg

• Headache
• Fever
• Nausea
• Dizziness
• Vomiting
• Back pain
• Diarrhea
• Muscle, joint, or bone pain

Common Side Effects

• Watering of the eyes
• Chills
• Fainting
• Tingling or numbness of the hands or feet
• Loosening of a tooth
• Pain in the mouth
• Fatigue
• Shortness of breath
• Muscle ache
• Kidney problems
• Numbness or a feeling of heaviness in the jaw
• Low level of red blood cells
• Low level of magnesium
• Potassium in the blood
• Abnormal blood counts

Dosage of Xolnic 4 mg Injection

Xolnic 4 mg Injection contains an active ingredient, Zoledronic Acid, which is used to treat or prevent the weakening of the bones (Osteoporosis). This medicine is readily available with all the leading pharmacies, drugstores, and medical supply stores; though, this medication should be taken on doctor’s prescription only. The patient must discuss with the medical doctor for an alteration of dosage & time of medicine, knowing the fact that the severity of the disease can vary from person to person. Your doctor can best judge this adjustment.

Adults are advised to take Xolnic 4 mg Injection at a fixed time with or without food as instructed by your medical doctor. You must take Xolnic 4 mg Injection regularly on time for better results.

How To Manage Side Effects?

• Communication
• Follow Dosage Instructions
• Pain Relief
• Rest and Recovery
• Hydration
• Anti-Nausea Medication
• Temperature Control
• Dietary Considerations
• Allergy Precautions
• Monitoring
• Support Network
• Avoid Alcohol and Tobacco
• Follow-up Appointments

Warning And Precaution

• Kidney/ Liver disease
• Allergy
• Infections
• This medicine is not suggested for use by children
• You must get your blood test done repeatedly during treatment to monitor the side effects of Zoledronic Acid on your blood cells
• Regular blood tests are essential to check your blood cells along with kidney, liver & heart function during treatment with this medicine
• You must drink plenty of fluids to prevent dehydration & kidney damage
• Use of this medicine can lower the level of calcium in the blood, so you must take calcium & vitamin D supplements as suggested by your doctor
• Use of this medicine may cause a rare condition called osteonecrosis of the jaw, so you must have regular dental check-ups & inform your doctor if you develop sudden pain in your jaw
• Your doctor will monitor response to this medicine by testing your bone mineral density (BMD). It is typically done every 1-3 years
• You should not drive or operate heavy machines besides taking this medicine as it may cause dizziness
• You are supposed not to take this drug if you are pregnant, planning to conceive or are breastfeeding
• You must always discuss with your medical doctor to obtain the first-rate treatment if you are observing a number of the conditions mentioned above.

Safety Advice

• Medical Supervision
• Allergy Check
• Pregnancy and Breastfeeding
• Medical History
• Dosage Compliance
• Needle Safety
• Monitoring
• Alcohol and Sedatives
• Driving and Operating Machinery
• Interactions
• Storage
• Disposal
• Emergency Contact
• Alternate Treatment Options

Frequently Asked Questions

 1. How does Xolnic 4 mg Injection 1’s work?