Intaxel 100mg Paclitaxel Injection

Introduction to Intaxel 100mg Injection

Intaxel 100 mg Injection is a chemotherapy medication that contains the active ingredient paclitaxel. It is primarily used to treat various types of cancers, including ovarian, breast, lung, and pancreatic cancers. As a member of the taxane class of drugs, Intaxel works by disrupting the normal function of microtubules during cell division, ultimately preventing the growth and spread of cancer cells.

Intaxel 100mg Injection contains Paclitaxel which belongs to a group of Anti-cancer medicines called Taxanes. This injection is administered intravenously under the supervision of a healthcare professional, typically in a hospital or clinical setting. The dosage and frequency depend on the type of cancer being treated, the patient’s body size, and their overall medical condition.

Pre-medications are often given before administering Intaxel to reduce the risk of allergic reactions, which can occur with this drug. Intaxel 100mg, manufactured by Fresenius Kabi India Pvt Ltd, contains the active ingredient Paclitaxel, a powerful chemotherapy medication used in the treatment of various types of cancer.

Uses of Intaxel 100 mg

• Breast Cancer
• Ovarian Cancer
• Pancreatic Cancer
• Kaposi’s Sarcoma
• NSCLC (non-small cell lung cancer)

How Does Intaxel 100 mg Injection Works?

Intaxel 100mg Injection works by interfering with the microtubule structures in the cell (substance which aids cancer cells to divide and multiply) thus inhibiting the growth of cancer cells and preventing its spread in affected individuals.

Side Effects of Intaxel 100

• Nausea and vomiting
• Hair loss (alopecia)
• Fatigue and weakness
• Diarrhea or constipation
• Mouth sores
• Loss of appetite

Dosage of Intaxel 100 mg

The dosage of Intaxel 100 mg Injection varies depending on the type of cancer, body surface area, and the patient’s overall health. Typically, it is given as an intravenous infusion over 3 hours once every 3 weeks, often in combination with other chemotherapy drugs.

Pre-medications such as corticosteroids and antihistamines are administered beforehand to minimize allergic reactions. The exact dose and schedule should always be determined by an oncologist based on individual treatment needs.

How to Manage Side Effects?

• Stay hydrated
• Eat small meals
• Use mild shampoos
• Practice good hygiene
• Rest regularly
• Wear soft shoes
• Report symptoms early

Drug Interactions

• Cisplatin
• Carboplatin
• Erythromycin and Ketoconazole
• Ritonavir and other protease inhibitors
• Warfarin and other blood thinners
• Phenytoin and Carbamazepine
• Live vaccines

Warnings & Precautions

1. Allergic Reactions:

• Severe hypersensitivity may occur; pre-medication is essential.

2. Bone Marrow Suppression:

• Monitor blood counts regularly to avoid complications.

3. Liver Impairment:

• Dose adjustments may be needed for liver dysfunction.

4. Heart Disorders:

• Caution in patients with cardiac history or arrhythmias.

5. Infections Risk:

• Low immunity can increase susceptibility to serious infections.

6. Pregnancy and Breastfeeding:

• Harmful to unborn baby; not recommended during breastfeeding.

7. Peripheral Neuropathy:

• Monitor for numbness or tingling in hands and feet.

8. Use by Professionals Only:

• Should be administered under trained medical supervision only.

Storage

• Store below 25°C (77°F) – Keep away from heat and sunlight.
• Do not freeze – Freezing may damage the medication’s effectiveness.
• Keep in original packaging – Protects from light and contamination.
• Keep out of children’s reach – Prevents accidental exposure or ingestion.
• Use before expiry date – Expired medication may be harmful or ineffective.
• Do not shake vial – Shaking can affect drug stability and performance.
• Dispose properly – Follow medical waste guidelines for unused medication.

Frequently Asked Questions

1. How should Intaxel 100 mg Injection be stored?

Intaxel 100 mg Injection should be stored according to the manufacturer’s instructions, typically in a controlled environment at the healthcare facility where it is administered. Patients should not need to store this medication at home.

2. Can I receive Intaxel 100 mg Injection if I am pregnant?

Intaxel can cause harm to an unborn baby, so it is not recommended for use during pregnancy. Women of childbearing potential should use effective contraception during treatment. It is also not recommended for breastfeeding mothers, as paclitaxel can pass into breast milk and harm a nursing infant.

3. What should I do if I miss a dose?

If you miss a dose of Intaxel, contact your healthcare provider immediately to reschedule. It is important not to skip doses or try to catch up on your own.

4. How to administer Intaxel 100mg Injection?

Intaxel 100mg Injection will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.