Metafort G 851 Tablets is a combination of Glimepiride and Metformin which belongs to a group of medicines called Antidiabetic agents. Metafort G 851 is used to treat type 2 diabetes mellitus when diet, exercise and the single agent does not result in adequate glycemic control. Type 2 diabetes is a chronic medical condition in which the body does not make enough insulin, or the produced insulin does not work well. Symptoms include excessive urination, excessive thirst, hunger, fatigue, and blurred vision.
Glimepiride lowers blood sugar by causing the pancreas to produce more insulin and helps the body use insulin efficiently. Metformin is a biguanide which effectively reduces the total amount of sugar released into the blood by the liver. Along treatment with Metafort G 851 follow regular exercise and diet plan as advised by your doctor to achieve better results.
Before taking Metafort G 851 inform your doctor if you have type 1 diabetes mellitus, diabetic ketoacidosis, severe liver or kidney disease, acute heart problems. Inform your doctor if you are pregnant or breastfeeding. It is not suitable for use in children and adolescents under 18 years of age. Avoid consumption of alcohol during treatment with Metafort G 851 as it may increase or decrease the blood sugar lowering action of Metafort G 851 and increases the risk of lactic acidosis. The most common side effects of taking Metafort G 851 are taste disturbance, nausea, diarrhea, stomachache, and vomiting. Contact your doctor if any of the symptoms worsen.
Uses of Metafort G 851
Treats type 2 Diabetesmellitus (when diet, exercise and the single agent does not result in adequate glycemic control)
How Does Metafort G 851 Works
Metafort G 851 controls blood glucose levels, where glimepiride works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin works by lowering glucose production in the liver, delaying glucose absorption from intestine, and increasing the body’s sensitivity to insulin.
Side Effects of Metafort G 851
Common Side Effects
Loss of appetite
Rare Side Effects
Low blood sugar levels (hypoglycemia)
Signs of reduced number of red blood cells (skin pale and weakness or breathlessness), platelets (easy bleeding or bruising) or white blood cells (repeated infections)
Read and follow the product’s safety data sheet (SDS) before use.
Store the product in a cool, dry, well-ventilated area away from direct sunlight.
Keep the product out of reach of children and pets.
Wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a mask when handling the product.
Avoid contact with skin, eyes, and clothing. In case of accidental contact, rinse affected area with plenty of water.
Do not ingest or inhale the product. If swallowed, seek medical attention immediately and provide SDS to medical personnel.
Do not mix Metafort-G 851 with other chemicals unless explicitly instructed to do so.
Use the product only in well-ventilated areas or use appropriate respiratory protection in confined spaces.
Avoid release of the product into the environment. Follow proper waste disposal regulations.
In case of a spill, contain the material and clean it up promptly according to the procedures outlined in the SDS.
If experiencing any adverse health effects after exposure, seek medical attention promptly and provide SDS to medical personnel.
Keep containers tightly closed when not in use.
Frequently Asked Questions
1. What are the recommended storage conditions for Metafort G 851 Tablet SR?
Ans. Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
2. Can the use of Metafort G 851 Tablet SR lead to lactic acidosis?
Ans. Yes, the use of Metafort G 851 Tablet SR can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is considered to be harmful for patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Metafort G 851 Tablet SR and consult your doctor immediately.
3. What is Metafort G 851 Tablet SR?
Ans. Metafort G 851 Tablet SR is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.
4. What are the possible side effects of Metafort G 851 Tablet SR?
Ans. The use of Metafort G 851 Tablet SR is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.