Introduction to Metafort 500 mg Tablets
Metafort 500 mg Tablets contain Metformin which belongs to the group of medicines called Anti-diabetic agents. It is used to treat Type II diabetes mellitus when diet and exercise alone do not result in adequate blood sugar control. Type II diabetes mellitus is a chronic disease characterized by abnormally high levels of glucose in the blood.
It is caused by inadequate production of a hormone called insulin (produced by the pancreas to metabolize glucose) or by reduced sensitivity of body cells to insulin.
Metafort 500 mg Tablets work by helping your body utilize more circulating blood glucose. It is suitable for use both in adults and in children (aged 10 years or older). Along with the treatment, your doctor might ask you to make certain lifestyle changes, such as following a healthy diet, exercising regularly, and avoiding alcohol.
Uses of Metafort 500 mg
- Type 2 Diabetes
- Blood Sugar Regulation
- Adjunct to Diet and Exercise
- Monotherapy or Combination Therapy
- Prevention of Diabetes Complications
- Polycystic Ovarian Syndrome (PCOS)
How Does Metafort 500 Work?
Metafort 500 mg Tablets are an antidiabetic medicine. It makes the body more sensitive to insulin (a hormone involved in glucose metabolism). This helps our body’s cells utilize more circulating blood glucose, thereby reducing blood sugar levels. Additionally, it also prevents glucose production by the liver and reduces its absorption in the body.
Side Effects of Metafort
Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Stomach discomfort or pain
- Loss of appetite
- Headache
Serious Side Effects
- Lactic Acidosis
- Hypoglycemia
- Allergic Reactions
- Liver Problems
- Blood Disorders
- Serious Skin Reactions
- Infections
Dosage of Metafort 500
- The usual starting dose is one tablet of Metafort 500 mg taken orally once a day.
- The tablet is typically taken with meals to reduce the risk of stomach upset.
- Your doctor may adjust the dosage based on your blood sugar levels and how well you respond to the medication.
- The maximum recommended daily dose is usually two tablets of Metafort 500 mg (1000 mg) per day, split into two doses (500 mg twice daily).
- For certain patients, the doctor may prescribe a lower starting dose to minimize side effects and gradually increase it if needed.
- Elderly individuals or those with kidney problems may require a dosage adjustment, which should be determined by their healthcare provider.
- If you miss a dose, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
- Never take a double dose to make up for a missed one.
Strengths and Variants
How to Manage Side Effects?
Warnings & Precautions
Here are important warnings and precautions for using Metafort 500 mg Tablets:
1. Kidney Function
- Metformin is cleared by kidneys; impaired function increases lactic acidosis risk.
2. Liver Health
- Liver disease may raise lactic acidosis risk; avoid if liver problems exist.
3. Hypoglycemia Risk
- Glimepiride can cause low blood sugar, especially if meals are skipped.
4. Surgery and Imaging Tests
- Stop medication before surgeries or contrast dye tests as directed.
5. Not for Type 1 Diabetes
- This drug is ineffective and unsafe for type 1 diabetes patients.
6. Vitamin B12 Monitoring
- Long-term use may lower vitamin B12; regular monitoring advised.
7. Pregnancy and Breastfeeding
- Not recommended unless prescribed; insulin preferred during pregnancy.
Storage
- Store at room temperature between 15°C to 30°C (59°F to 86°F).
- Keep the tablet in its original packaging to protect from moisture and light.
- Store in a cool, dry place, away from direct sunlight and humidity.
- Keep out of reach of children and pets.
- Do not use after the expiration date printed on the package.
- Dispose of expired or unused medicine safely according to local guidelines.









Davion –
helped me with great and fast service
Nongk ynrih –
This product is very effective and it has helped me a lot.