Introduction to Deczuba 50 mg Injection
Deczuba 50mg Injection is used in the treatment of blood cancer called Acute Myeloid Leukaemia (AML). It is also used to treat patients with myelodysplastic syndrome (MDS). It may be used to treat other conditions, as determined by the doctor.
Deczuba 50mg Injection is also used with certain other medicines as part of combination chemotherapy. It is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, fever and lung infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Deczuba 50 mg
- Myelodysplastic syndrome
- Blood cancer
How Does Deczuba 50 Works
Deczuba 50 mg Injection has an active ingredient; Decitabine. Decitabine is a hypomethylating agent which hypomethylates DNA by inhibiting DNA methyltransferase. Decitabine incorporates into DNA strands upon replication. After that when DNA methyltransferases (DNMTs), are engaged to bind to the DNA & to replicate the methylation to the daughter strand, DNMTs are bound to Decitabine irretrievably & cannot disengage.
Therefore, the action of Decitabine is division-dependant, which means the cells have to divide in order for the pharmaceutical to act. Therefore, cancer cells which divide much faster than most other cells in the body will be severely affected by Decitabine because they replicate more.
Side Effects of Deczuba 50
- Excessive tiredness and weakness
- Pale and clammy skin
- Headache and dizziness
- Mental confusion
- Fast/irregular heart beat
- Difficulty in falling or staying asleep
- Shortness of breath
- Nausea or vomiting
Dosage of Deczuba 50 mg
Deczuba 50 mg Injection contains an active ingredient, Decitabine, which is used in the treatment of ovarian cancer, head & neck cancer, Testicular cancer, cervical cancer, breast cancer, blood cancer, non-Hodgkin lymphoma (NHL), lung cancer, bone cancer & urinary bladder cancer. This medicine is accessible in different substitutes & strengths & must be purchased or given on doctor’s prescription only. You must consult your physician for dosage and time because age and severity of the disease differ from person to person and it can only be judged by your doctor.
Adults are advised to take Deczuba 50 mg Injection at a fixed time with or without food as instructed by your Doctor. You must take Deczuba 50 mg Injection regularly on time for better results.
Warning & Precautions
- Liver/kidney disease
- Regular monitoring of complete blood cell counts and kidney function is necessary during treatment with this medicine
- You must not drive or operate heavy machinery while taking this medicine as it may cause nausea and vomiting
- You must use a reliable contraceptive method to prevent pregnancy while you are taking this medicine
- Always consult with your doctor straight away to get best possible treatment if you are observing any of the above mentioned conditions
Frequently Asked Questions
1. Is Deczuba 50mg Injection a vesicant?
Ans. Deczuba 50mg Injection is not a vesicant and is not known to cause severe local tissue damage upon extravasation (leaking of injected Deczuba 50mg Injection into the surrounding tissues from the site of administration) when injected.
2. How effective is Deczuba 50mg Injection?
Ans. The effectiveness of Deczuba 50mg Injection depends upon several factors including the patient’s clinical condition, number of treatment cycles etc. and may vary depending upon the individual response.
3. Does Deczuba 50mg Injection cause hair loss?
Ans. Yes. Hair loss (alopecia) is among the known side effects of Deczuba 50mg Injection.
4. How is Deczuba 50mg Injection administered?
Ans. Deczuba 50mg Injection comes as a powder to be to be added to fluid and injected slowly over 3 hours into a vein (slow i.v infusion) by a doctor who is experienced in giving chemotherapy medications for cancer in a hospital or a clinic.