Introduction to Spegra Tablets
Spegra Tablet is a combination of antiretroviral medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).
Spegra Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine can be taken with or without food. Taking these medicines regularly at the same time increases their effectiveness.
A dose of this medicine should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it. Sudden discontinuation of the treatment may affect the potency of the medicine.
Uses of Spegra Tablets
Spegra Tablets are used in the management of HIV-1 infection in adults and adolescents weighing at least 35 kg. It is a fixed-dose combination of Dolutegravir, Emtricitabine, and Tenofovir Alafenamide, and is prescribed as a part of antiretroviral therapy (ART). Below are its key uses:
- Treatment of HIV-1 Infection
- Helps Achieve and Maintain Viral Suppression
- Boosts Immune Function
How Does Spegra Tablet Works?
Spegra Tablet combines three powerful antiretroviral agents: Dolutegravir, Emtricitabine, and Tenofovir Alafenamide. Together, these drugs work at different stages of the HIV replication cycle, making it harder for the virus to multiply and infect new cells in the body.
Dolutegravir is an integrase inhibitor that blocks the HIV enzyme integrase, preventing viral DNA from integrating into human DNA. This step is essential for the virus to multiply, and by blocking it, Dolutegravir stops the spread of HIV within the immune system.
Emtricitabine and Tenofovir Alafenamide are nucleoside reverse transcriptase inhibitors (NRTIs). They mimic natural building blocks of viral DNA and interfere with the reverse transcription process, causing premature termination of HIV replication. This significantly lowers the viral load in the bloodstream.
Side Effects of Spegra Tablet
Common Side Effects
- Headache
- Dizziness
- Mild nausea or upset stomach
- Joint or back discomfort
- Slight weight changes
- Sleepiness or tiredness
Rare but Serious Side Effects
- Chest pain or difficulty breathing
- Yellowing of the eyes or skin
- Unusual swelling (face, feet, or legs)
- Dark urine or black stools
- Persistent fever or chills
Dosage of Spegra Tablet
Missed Dose
Overdose
In case of an overdose of Spegra Tablet, seek immediate medical attention. Symptoms may include headache, nausea, fatigue, or dizziness. Do not attempt to take extra doses to make up for a missed one, as this can increase the risk of serious side effects.
Warnings & Precautions
1. Not Recommended Without Medical Supervision
- Spegra should only be taken under the supervision of a qualified healthcare provider experienced in HIV management.
2. Avoid In Pregnancy Without Medical Advice
- Use in pregnancy should be discussed with a doctor, as safety data is limited and benefits must outweigh potential risks.
3. May Cause Weight Gain or Fat Changes
- Some patients may experience weight gain or changes in body fat distribution while on long-term antiretroviral therapy.
4. Do Not Discontinue Suddenly
- Abrupt discontinuation may lead to viral rebound and resistance. Always consult your doctor before stopping Spegra.
5. Inform About All Other Medications
- Spegra can interact with other drugs, including antacids and certain antibiotics—inform your doctor about all medications and supplements.
Storage
- Store at room temperature between 20°C to 25°C.
- Keep the tablets in the original container with the lid tightly closed.
- Protect from moisture, heat, and direct sunlight.
- Do not store in the bathroom or other damp areas.
- Keep out of reach of children and pets.
- Do not use the tablets after the expiration date.
Frequently Asked Questions
1. How Long Should I Take Spegra Tablets?
Ans. The dose and duration of the medication depend upon the response to treatment. Follow your doctor’s advice and do not stop medications on your own.
2. Can Spegra Tablet 30’S Cure Hiv?
Ans. Spegra Tablet 30’S is not a cure for HIV. It is an antiretroviral medication that helps control the virus, reduce its replication, and slow down the progression of the disease. It is essential to continue taking the medication as prescribed, even if you feel well, to maintain viral suppression and protect your immune system.
3. Does Spegra Tablet 30’S Affect The Liver?
Ans. People with liver disease, including chronic hepatitis B or C taking antiretroviral have a higher risk of severe and potentially fatal liver complications. If you have hepatitis B infection, your doctor will carefully consider the best treatment regimen for you.
4. Is It Safe To Abruptly Stop Taking Spegra Tablet 30’S?
Ans. Abruptly stopping Spegra Tablet 30’S without medical guidance can lead to viral rebound and a decrease in treatment effectiveness. It is important to consult with your healthcare provider before changing your HIV treatment regimen.
Dordji Polina –
The product works really wonderfully if you take it right and follow the instructions how to take it and the delivery was on time. For what I paid for the product I feel I got my money worth.