Hertraz 440mg Injection

Introduction to Hertraz 440 mg Injection

Hertraz 440 mg Injection is a medication used in the treatment of certain types of breast and stomach cancers. It contains trastuzumab, a monoclonal antibody that specifically targets the human epidermal growth factor receptor 2 (HER2). HER2-positive cancers grow more aggressively, and Hertraz helps slow their progression by blocking HER2 receptors and inhibiting cancer cell growth.

This injection is commonly prescribed for HER2-positive metastatic breast cancer, early-stage breast cancer, and HER2-positive metastatic gastric cancer. It is often used in combination with chemotherapy or other cancer treatments to improve effectiveness. Doctors administer it as an intravenous (IV) infusion under strict medical supervision in a hospital or clinical setting.

The dosage and treatment duration depend on the patient’s condition, weight, and response to therapy. Hertraz is usually given once every one to three weeks. The first dose is infused slowly to monitor for allergic reactions, while subsequent doses may be administered more quickly if well tolerated.

Uses of Hertraz 440 mg 

Hertraz 440mg Injection, containing trastuzumab, is used primarily for the treatment of cancers that are characterized by the overexpression of the HER2 protein. Its main uses include:

• HER2-Positive Breast Cancer
• HER2-Positive Gastric Cancer
• Early-Stage HER2-Positive Breast Cancer
• Adjuvant Therapy
• Neoadjuvant Therapy

How Does Hertraz 440 Works? 

Hertraz 440 mg Injection works by targeting the HER2 protein, which is overexpressed in some breast and stomach cancers. HER2 plays a key role in cancer cell growth and division. Trastuzumab, the active ingredient in Hertraz, binds to HER2 receptors on the surface of cancer cells, blocking their ability to receive growth signals. This slows down or stops the uncontrolled proliferation of cancer cells.

In addition to blocking HER2 signaling, Hertraz also stimulates the immune system to attack cancer cells. It triggers a response where immune cells recognize and destroy HER2-positive cancer cells more effectively. This dual action—blocking growth signals and enhancing immune response—makes Hertraz a powerful targeted therapy.

Side Effects of Hertraz 440

Common Side Effects 

• Infusion-Related Reactions
• Nausea and Vomiting
• Fatigue
• Diarrhea
• Rashes
• Heart Issues
• Low Blood Cell Counts
• Infection Risk

Serious Side Effects.

• Severe Infusion Reactions
• Pulmonary Issues
• Serious Infections
• Hepatic Issues
• Severe Blood Cell Count Abnormalities

Dosage of Hertraz 440 mg

Hertraz 440 mg Injection contains an active ingredient, Trastuzumab, which is used in the treatment of breast cancer and stomach cancer. This medicine is available in various strengths and substitutes & must be given on doctor’s prescription only.

You should consult your doctor for dosage and time because age and severity of the disease differ from person to person and it can only be judged by your doctor. Adults are advised to take Hertraz 440 mg Injection at a fixed time with or without food as instructed by your Doctor. You must take this medicine regularly on time for better results.

Other Dosages of Hertraz 440mg

• Hertraz 150mg

How to Manage Side Effects?

• Consult with Healthcare Professional
• Follow Dosage Instructions
• Pre-medication for Infusion Reactions
• Monitor for Allergic Reactions
• Managing Infusion-Related Reactions

Warning & Precautions

1. Heart Complications:

• Hertraz can cause serious heart problems, including heart failure and reduced heart function. Patients with a history of heart disease should be closely monitored through regular heart function tests (e.g., echocardiogram).

2. Infusion Reactions:

• Some patients may experience severe infusion-related reactions such as fever, chills, difficulty breathing, or low blood pressure during or after the injection. The first dose is given slowly to monitor for any adverse reactions.

3. Lung Toxicity:

• Hertraz may cause lung-related side effects, including difficulty breathing, lung inflammation, or fluid buildup in the lungs. Patients with pre-existing lung conditions should inform their doctor before starting treatment.

4. Pregnancy & Breastfeeding:

• Hertraz can harm an unborn baby and should not be used during pregnancy. Women of childbearing age should use effective contraception during and for at least 7 months after treatment. Breastfeeding should also be avoided during therapy.

5. Liver & Kidney Function:

• Patients with liver or kidney disease should use Hertraz with caution, as impaired organ function may affect drug metabolism and increase the risk of side effects. Regular blood tests may be required to monitor overall health.

Safety Advice

• Administered by Healthcare Professionals
• Medical History Disclosure
• Monitoring During Infusion
• Cardiac Function Monitoring
• Avoid Live Vaccines
• Regular Follow-up
• Do Not Self-Administer

Frequently Asked Questions

1. What are the serious side effects of Hertraz 440mg Injection?

Ans. There are various side effects related to Hertraz 440mg Injection such as sore throat, fever, chills, excessive tiredness, pale skin, nosebleeds, and other unusual bruising or bleeding. One can also experience stomach pain, seizures, hallucinations, muscle cramps, and spasms. Along with that, nausea or vomiting, loss of appetite, fatigue, rapid heart beat, discoloration of urine; decreased amount of urine, difficulty in urinating, pain when urinating, and other signs of infection can also be observed with the use of Hertraz 440mg Injection. You should call your doctor immediately if you notice any such symptoms.

2. How long after Hertraz 440mg Injection therapy can I get pregnant?

Ans. Women of child-bearing age should use effective contraception during Hertraz 440mg Injection therapy and for 7 months after completing the treatment. You can plan your pregnancy after 7 months of treatment with Hertraz 440mg Injection.

3. How long should Hertraz 440mg Injection be taken?

Ans. Patients with early breast cancer should take Hertraz 440mg Injection for 1 year or until disease recurs, whichever occurs first. It is not advised to extend the treatment beyond 1 year in patients of early breast cancer.

4. Is fasting required before administering Hertraz 440mg Injection?

Ans. No, fasting is not required before administering Hertraz 440mg Injection. It should be given under the guidance of a doctor who is experienced in giving cancer chemotherapy and should be given only by a healthcare professional.