Intaxel 100mg Injection

Introduction to Intaxel 100 mg Injection

Intaxel 100mg Injection contains Paclitaxel which belongs to a group of Anti-cancer medicines called Taxanes. Intaxel 100mg Injection is used to treat ovarian and breast cancer as a first line of therapy and as a second line of treatment when platinum containing medicines (such as cisplatin) or anthracyclines are insufficient to treat the disease in affected individuals.

Intaxel 100mg, manufactured by Fresenius Kabi India Pvt Ltd, contains the active ingredient Paclitaxel, a powerful chemotherapy medication used in the treatment of various types of cancer.

Uses of Intaxel 100 mg 

• Treats ovarian and breast cancer.
• Treats advanced NSCLC (non-small cell lung cancer)
• Treats AIDS-related Kaposi’s sarcoma in affected individuals.

How Does Intaxel 100 mg Injection Works?

Intaxel 100mg Injection works by interfering with the microtubule structures in the cell (substance which aids cancer cells to divide and multiply) thus inhibiting the growth of cancer cells and preventing its spread in affected individuals.

Side Effects of Intaxel 100

• Minor allergic reactions such as flushing, rash and/or itching
• Infections such as upper respiratory infection, urinary tract infection
• Shortness of breath
• Sore throat/mouth ulcers, sore and red mouth
• Diarrhea, nausea, vomiting
• Loss of hair
• Pain in the muscles, cramps, joints
• Fever, severe chills, headache, dizziness, tiredness, looking pale
• Bleeding, bruising more easily than normal

Common Side Effects

• Nausea and Vomiting
• Hair Loss (Alopecia)
• Decreased Blood Cell Counts
• Fatigue
• Peripheral Neuropathy
• Joint and Muscle Pain
• Mouth Sores
• Diarrhea
• Allergic Reactions
• Changes in Liver Function Tests
• Changes in Liver Function Tests

 Serious Side Effects

• Severe Allergic Reactions (Anaphylaxis)
• Severe Neutropenia
• Severe Peripheral Neuropathy
• Cardiovascular Issues
• Severe Gastrointestinal Symptoms
• Severe Liver Dysfunction
• Interstitial Pneumonitis
• Severe Myelosuppression
• Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

 Rare Side Effects

• Severe Skin Reactions
• Pneumonitis
• Myopathy and Rhabdomyolysis
• Vision Changes
• Severe Cardiovascular Events
• Cystoid Macular Edema
• Hemolytic Anemia
• Severe Peripheral Edema
• Alopecia Universalis
• Acute Respiratory Distress Syndrome (ARDS)
• Severe Hypersensitivity Reactions
• Secondary Malignancies

Dosage of Intaxel 100 mg

Intaxel 100 mg/ 16.67 ml Injection contains an active ingredient, Paclitaxel, which is used in the treatment of breast cancer, non-small cell lung cancer and pancreatic cancer. This medicine is available in various strengths and substitutes & must be given on doctor’s prescription only. You should consult your doctor for dosage and time because age and severity of the disease differ from person to person and it can only be judged by your doctor.

Adults are advised to take Intaxel 100 mg/ 16.67 ml Injection at a fixed time with or without food as instructed by your Doctor. You must take this medicine regularly on time for better results

How to Manage Side Effects?

• Consult with Healthcare Provider
• Allergic Reactions
• Nausea and Vomiting
• Hair Loss
• Fatigue
• Peripheral Neuropathy
• Muscle and Joint Pain

Warning & Precautions

• Allergy
• Liver/kidney disease
• You must use two methods of contraception while on this therapy & 3 months after it to avoid pregnancy
• You must get your regular blood tests done to monitor your blood cells and liver function during treatment with this medicine
• You should not drive or operate machinery while taking this medicine as it may cause dizziness
• You must always consult your doctor immediately to get the best possible treatment when you are suffering from any of the above-mentioned conditions.

Safety Advice

• Medical Supervision: Intaxel 100 should be administered by a qualified healthcare professional in a hospital or clinical setting. Do not attempt to self-administer this medication.
• Allergic Reactions: Inform your doctor about any known allergies or hypersensitivity to paclitaxel or other medications. If you experience signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, seek immediate medical attention.
• Pregnancy and Breastfeeding: Intaxel 100 may cause harm to the fetus and is generally not recommended during pregnancy. If you are pregnant or planning to become pregnant, discuss the risks and benefits with your doctor. Avoid breastfeeding while on this medication.
• Blood Cell Counts: Regularly monitor your blood cell counts during treatment. Paclitaxel can cause a decrease in blood cell production, leading to an increased risk of infections, anemia, and bleeding.

Frequently Asked Questions

1. How should Intaxel 100 mg Injection be stored?

Ans. Intaxel 100 mg Injection should be stored according to the manufacturer’s instructions, typically in a controlled environment at the healthcare facility where it is administered. Patients should not need to store this medication at home.

2. Can I receive Intaxel 100 mg Injection if I am pregnant or breastfeeding?

Ans. Intaxel can cause harm to an unborn baby, so it is not recommended for use during pregnancy. Women of childbearing potential should use effective contraception during treatment. It is also not recommended for breastfeeding mothers, as paclitaxel can pass into breast milk and harm a nursing infant.

3. What should I do if I miss a dose?

Ans. If you miss a dose of Intaxel, contact your healthcare provider immediately to reschedule. It is important not to skip doses or try to catch up on your own.

4. How to administer Intaxel 100mg Injection?

Ans. Intaxel 100mg Injection will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.