Synthivan Tablet

Introduction to Synthivan Tablet

Atazanavir is a medication used to treat HIV infection, and it is available under different brand names depending on the pharmaceutical manufacturer. However, as of my last update, “Synthivan” was not one of the recognized brand names for Atazanavir.

Synthivan tablets are a combination medication used in the treatment of HIV-1 infection in adults. Each tablet contains two active ingredients: Atazanavir (300 mg) and Ritonavir (100 mg). Atazanavir is a protease inhibitor that works by blocking the action of HIV protease enzyme, thereby preventing the virus from multiplying in the body. Ritonavir is included in the formulation to increase the levels of atazanavir in the bloodstream, enhancing its effectiveness.

Synthivan is typically prescribed as part of a combination antiretroviral therapy (ART) regimen, which may include other medications to effectively control HIV-1 infection. It is important to take Synthivan exactly as prescribed by your healthcare provider, usually once daily with food. This medication helps to reduce the viral load in the blood, improve immune function, and delay the progression of HIV-related illnesses when used consistently and correctly.

Uses of Synthivan Tablet

Atazanavir is a protease inhibitor that is commonly used as part of antiretroviral therapy (ART) for the management of HIV (Human Immunodeficiency Virus) infection. When used in combination with other antiretroviral drugs, Atazanavir helps to suppress the replication of the virus, reduce its viral load in the body, and maintain the overall health of the patient. By doing so, it slows down the progression of HIV to AIDS (Acquired Immunodeficiency Syndrome).

If “Synthivan” is indeed a new fixed-dose combination medication, its specific uses and indications would depend on the formulation and combination with other drugs. Fixed-dose combinations are often used to simplify treatment regimens and improve adherence to medication in the management of chronic conditions like HIV.

To get accurate and up-to-date information about the uses of “Synthivan Atazanavir” or any other medication, it is essential to refer to official drug references, consult healthcare professionals, or visit the official website of the pharmaceutical company that manufactures the product.

How Does Synthivan Works?

• Inhibition of Protease: Atazanavir works by inhibiting the protease enzyme. Specifically, it binds to the active site of the HIV protease enzyme, preventing it from properly functioning.
• Blockage of Viral Maturation: Without functional protease, the newly formed viral particles remain immature and non-infectious.
• Reduction of Viral Load: As a result of the inhibited protease, the production of mature and infectious HIV particles is significantly reduced.
• Viral Replication Suppression: By decreasing the number of infectious viral particles in the body, Atazanavir helps to slow down the replication of the virus and its progression in the body.

Side Effects of Synthivan Tablet

• Nausea
• Diarrhea
• Headache
• Fatigue
• Insomnia
• Abdominal Pain
• Rash
• Changes in Appetite
• Elevated Liver Enzymes

Serious Side Effects

• Liver Problems
• Pancreatitis
• Changes in Heart Rhythm
• Allergic Reactions
• Hyperbilirubinemia
• Metabolic Effects
• Kidney Problems
• Fat Redistribution
• Immune Reconstitution Inflammatory Syndrome (IRIS)
• Bone Loss

Rare Side Effects

• Blood Disorders
• Vision Changes
• Rhabdomyolysis
• Neurological Symptoms
• Gastrointestinal Effects
• Endocrine Effects
• Respiratory Effects

Dosage of Synthivan Tablet

• The dosage of Atazanavir can vary depending on the specific formulation, the combination with other drugs, the patient’s age, weight, kidney function, and the severity of the HIV infection. Dosage should always be determined and prescribed by a qualified healthcare professional.
• Atazanavir is usually taken once daily, with or without food. If it is combined with other antiretroviral medications, the dosing schedule and instructions may differ. Always follow the healthcare provider’s recommendations regarding when and how to take the medication.
• Atazanavir should not be taken with food that is high in fat as it can reduce the absorption of the drug. In some cases, it may be co-administered with a small amount of low-fat food or a buffered antacid to enhance absorption.
• It is crucial to adhere to the prescribed dosage and not miss any doses. Consistent and regular intake of antiretroviral medications is essential for the effectiveness of HIV treatment.
• Dosage adjustments may be necessary if there are drug interactions with other medications the patient is taking or if there are underlying health conditions that may affect the metabolism or clearance of Atazanavir from the body.

How to Manage Side Effects?

• Communicate with Healthcare Provider
• Adhere to Dosage and Schedule
• Do Not Discontinue Abruptly
• Report Severe Side Effects Promptly
• Stay Hydrated
• Take with Food (if recommended)
• Manage Nausea and Vomiting
• Use Sunscreen
• Manage Rash
• Monitor Liver Function
• Avoid Alcohol and Certain Drugs

Warning & Precautions

• Drug Interactions
• Allergic Reactions
• Liver Function
• Heart Rhythm Abnormalities
• Hyperbilirubinemia
• Pancreatitis
• Diabetes
• Immune Reconstitution Inflammatory Syndrome (IRIS)
• Pregnancy and Breastfeeding
• Kidney Function

Safety Advice

• Drug Interactions: Atazanavir may interact with other medications, including over-the-counter drugs, supplements, and herbal products. Inform your healthcare provider about all medications you are taking to prevent potential interactions.
• Allergic Reactions: If you have known allergies or hypersensitivity to Atazanavir or any other components of “Synthivan Atazanavir,” discuss this with your healthcare provider before starting treatment.
• Liver Function: Atazanavir can cause liver-related side effects. Regular monitoring of liver function is important, especially for individuals with pre-existing liver conditions.
• Heart Rhythm Abnormalities: Atazanavir may prolong the QT interval, which could lead to abnormal heart rhythms. Individuals with a history of heart problems or taking other medications that also affect the QT interval may require special monitoring.
• Hyperbilirubinemia: Atazanavir is known to cause elevated levels of bilirubin in the blood, leading to jaundice (yellowing of the skin and eyes). While this side effect is generally harmless, it can cause cosmetic concerns.

Frequently Asked Questions

1. What should I do if I miss a dose of Synthivan?

Ans. If you miss a dose of Synthivan, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take double doses to make up for a missed dose.

2. Where can I get more information about Synthivan?

Ans. For more information about Synthivan, including specific dosing guidelines, potential side effects, and interactions, consult your healthcare provider or pharmacist. They can provide personalized advice based on your medical history and individual needs.

3. What are the common uses of Atazanavir?

Ans. Atazanavir is primarily used as part of combination therapy for the treatment of HIV-1 infection in adults and children above a certain age and weight. It is usually prescribed in combination with other antiretroviral drugs to achieve better treatment outcomes.

4. How should I take Atazanavir tablets?

Ans. The specific dosing instructions for Atazanavir can vary based on factors such as the patient’s age, weight, other medications being taken, and the individual’s response to treatment. It is essential to follow the dosing instructions provided by your healthcare provider or as indicated in the product information. Atazanavir is usually taken with food to enhance absorption.