Synthivan Tablet

Introduction to Synthivan Tablet

Atazanavir is a medication used to treat HIV infection, and it is available under different brand names depending on the pharmaceutical manufacturer. However, as of my last update, “Synthivan” was not one of the recognized brand names for Atazanavir.

It’s possible that new medications or brand names have emerged since my last update, or “Synthivan” may be a product available in specific regions or countries where my data does not cover.

To get accurate and up-to-date information about “Synthivan Tablets,” I recommend consulting a healthcare professional or a reliable medical source in your region. They will be able to provide you with the most current and relevant information about this medication.

Synthivan Tablet is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).

Synthivan Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine should be taken with food. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it. Sudden discontinuation of the treatment may affect the potency of the medicine.

Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any health condition. Your doctor may suggest regular laboratory tests to check your blood counts, kidney and liver functions, and other health conditions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods in order to prevent transmission of HIV during intercourse.

Common side effects of this medicine are headache, nausea, vomiting, diarrhea, stomach pain, taste change, skin rash, tingling and numbness of feet and hand, etc. These side effects are generally temporary, but if they persist or become serious inform your doctor. This medicine can also make you feel dizzy or sleepy, so it is advised to avoid driving. Drinking plenty of fluid can help you to cope up with this side effect, so stay hydrated.

Uses of Synthivan Tablet

Atazanavir is a protease inhibitor that is commonly used as part of antiretroviral therapy (ART) for the management of HIV (Human Immunodeficiency Virus) infection. When used in combination with other antiretroviral drugs, Atazanavir helps to suppress the replication of the virus, reduce its viral load in the body, and maintain the overall health of the patient. By doing so, it slows down the progression of HIV to AIDS (Acquired Immunodeficiency Syndrome).

If “Synthivan” is indeed a new fixed-dose combination medication, its specific uses and indications would depend on the formulation and combination with other drugs. Fixed-dose combinations are often used to simplify treatment regimens and improve adherence to medication in the management of chronic conditions like HIV.

To get accurate and up-to-date information about the uses of “Synthivan Atazanavir” or any other medication, it is essential to refer to official drug references, consult healthcare professionals, or visit the official website of the pharmaceutical company that manufactures the product.

How Does Synthivan Works

• Inhibition of Protease: Atazanavir works by inhibiting the protease enzyme. Specifically, it binds to the active site of the HIV protease enzyme, preventing it from properly functioning.
• Blockage of Viral Maturation: Without functional protease, the newly formed viral particles remain immature and non-infectious.
• Reduction of Viral Load: As a result of the inhibited protease, the production of mature and infectious HIV particles is significantly reduced.
• Viral Replication Suppression: By decreasing the number of infectious viral particles in the body, Atazanavir helps to slow down the replication of the virus and its progression in the body.

Side Effects of Synthivan Tablet

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain or discomfort
• Headache
• Rash
• Elevated bilirubin levels (hyperbilirubinemia), which may cause yellowing of the skin and eyes (jaundice)
• Elevated liver enzymes
• Fatigue or weakness
• Changes in taste perception
• Insomnia or sleep disturbances
• Increased blood sugar levels (hyperglycemia)
• Lipodystrophy (changes in body fat distribution)
• Changes in blood lipid levels (cholesterol and triglycerides)

Serious Side Effects

• Severe rash or skin reactions
• Liver problems or hepatitis (inflammation of the liver)
• Pancreatitis (inflammation of the pancreas)
• Changes in heart rhythm (prolongation of QT interval)
• Allergic reactions, including angioedema (swelling of the face, lips, tongue, or throat)
• Severe nausea, vomiting, or abdominal pain
• Signs of kidney problems, such as changes in urination or swelling in the feet and ankles
• Signs of hyperglycemia (high blood sugar), including increased thirst, frequent urination, and fatigue
• Signs of anemia (low red blood cell count), such as fatigue, weakness, and pale skin
• Muscle pain or weakness
• Unexplained bleeding or bruising
• Yellowing of the skin or eyes (jaundice)

Rare Side Effects

• Stevens-Johnson syndrome (a severe skin condition)
• Toxic epidermal necrolysis (a life-threatening skin disorder)
• Immune reconstitution inflammatory syndrome (IRIS) – can occur when the immune system starts to recover, leading to an exaggerated inflammatory response
• Severe hypersensitivity reactions
• Hemolytic anemia (destruction of red blood cells)
• Hemorrhagic colitis (inflammation and bleeding of the colon)
• Redistribution or accumulation of body fat (lipodystrophy)
• Metabolic disturbances, including lactic acidosis
• Osteonecrosis (death of bone tissue due to poor blood supply)

Dosage of Synthivan Tablet

• The dosage of Atazanavir can vary depending on the specific formulation, the combination with other drugs, the patient’s age, weight, kidney function, and the severity of the HIV infection. Dosage should always be determined and prescribed by a qualified healthcare professional.
• Atazanavir is usually taken once daily, with or without food. If it is combined with other antiretroviral medications, the dosing schedule and instructions may differ. Always follow the healthcare provider’s recommendations regarding when and how to take the medication.
• Atazanavir should not be taken with food that is high in fat as it can reduce the absorption of the drug. In some cases, it may be co-administered with a small amount of low-fat food or a buffered antacid to enhance absorption.
• It is crucial to adhere to the prescribed dosage and not miss any doses. Consistent and regular intake of antiretroviral medications is essential for the effectiveness of HIV treatment.
• Dosage adjustments may be necessary if there are drug interactions with other medications the patient is taking or if there are underlying health conditions that may affect the metabolism or clearance of Atazanavir from the body.

How to Manage Side Effects

• Communicate with Healthcare Provider
• Adhere to Dosage and Schedule
• Do Not Discontinue Abruptly
• Report Severe Side Effects Promptly
• Stay Hydrated
• Take with Food (if recommended)
• Manage Nausea and Vomiting
• Use Sunscreen
• Manage Rash
• Monitor Liver Function
• Avoid Alcohol and Certain Drugs

Warning & Precautions 

• Drug Interactions
• Allergic Reactions
• Liver Function
• Heart Rhythm Abnormalities
• Hyperbilirubinemia
• Pancreatitis
• Diabetes
• Immune Reconstitution Inflammatory Syndrome (IRIS)
• Pregnancy and Breastfeeding
• Kidney Function

Safety Advice

• Drug Interactions: Atazanavir may interact with other medications, including over-the-counter drugs, supplements, and herbal products. Inform your healthcare provider about all medications you are taking to prevent potential interactions.
• Allergic Reactions: If you have known allergies or hypersensitivity to Atazanavir or any other components of “Synthivan Atazanavir,” discuss this with your healthcare provider before starting treatment.
• Liver Function: Atazanavir can cause liver-related side effects. Regular monitoring of liver function is important, especially for individuals with pre-existing liver conditions.
• Heart Rhythm Abnormalities: Atazanavir may prolong the QT interval, which could lead to abnormal heart rhythms. Individuals with a history of heart problems or taking other medications that also affect the QT interval may require special monitoring.
• Hyperbilirubinemia: Atazanavir is known to cause elevated levels of bilirubin in the blood, leading to jaundice (yellowing of the skin and eyes). While this side effect is generally harmless, it can cause cosmetic concerns.

Frequently Asked Questions

1. What is Atazanavir?

Ans. Atazanavir is an antiretroviral medication used to treat HIV (human immunodeficiency virus) infection. It belongs to a class of drugs known as protease inhibitors. Atazanavir helps lower the amount of HIV in the body and supports the immune system in fighting the virus.

2. How does Atazanavir work?

Ans. Atazanavir works by inhibiting the activity of the HIV protease enzyme. This enzyme is responsible for cutting large HIV polyproteins into smaller functional proteins that are necessary for the virus to replicate. By blocking this action, Atazanavir helps prevent the production of new infectious HIV particles.

3. What are the common uses of Atazanavir?

Ans. Atazanavir is primarily used as part of combination therapy for the treatment of HIV-1 infection in adults and children above a certain age and weight. It is usually prescribed in combination with other antiretroviral drugs to achieve better treatment outcomes.

4. How should I take Atazanavir tablets?

Ans. The specific dosing instructions for Atazanavir can vary based on factors such as the patient’s age, weight, other medications being taken, and the individual’s response to treatment. It is essential to follow the dosing instructions provided by your healthcare provider or as indicated in the product information. Atazanavir is usually taken with food to enhance absorption.