Introduction to Vivitra 150 mg Injection
Vivitra 150mg Injection is used in the treatment of breast and stomach Cancer. It works by killing the cancer cells by inhibiting HER2 (human epidermal growth factor receptor protein).
In HER 2 positive patients, the breast cancer cells are mostly composed of HER2 proteins that cause rapid development of cancer tumor by serving as a signal to the cancerous.
This medication is also used to treat metastatic gastric cancer with increased levels of HER2 proteins. Her 2 positive breast cancer are most aggressive in nature. The targeted therapy for her 2 positive breast cancer works by selectively targeting the proteins that are responsible for the growth, development, and spread of cancer.
Use effective birth control during the treatment and for at least 7 months after the final dose. Vivitra 150mg Injection is not recommended for patients aged under 18, patients who have severe breathing problems or need oxygen treatment.
Uses of Vivitra 150 mg
Vivitra 150 mg is a brand name for trastuzumab, a monoclonal antibody used primarily in the treatment of HER2-positive cancers. Here’s a summary of its uses:
- Breast Cancer
- Gastric (Stomach) Cancer
How Does Vivitra 150 Works?
Vivitra 150mg Injection is a recombinant IgG1 monoclonal antibody. It works against the HER2 (human epidermal growth factor receptor protein) receptors which are responsible for the over-proliferation of cancer cells in breast cancer and stomach cancer cells. It destroys the cancer cells by inhibiting HER2. It also inhibits various cancer-causing downstream signaling pathways.
Dosages of Vivitra 150mg Injection
Side Effects of Vivitra 150
Common Side Effects
- Fever and Chills
- Nausea and Vomiting
- Fatigue (Tiredness)
- Diarrhea
- Headache
- Rash or Skin Reactions
- Cough or Respiratory Symptoms
- Muscle or Joint Pain
Serious Side Effects
- Severe Allergic
- Severe Infections
- Liver Toxicity
- Gastrointestinal Issues
Drug Interactions
- Anthracyclines
- Other Chemotherapy Drugs
- Radiation Therapy
- Immunosuppressants or Biologics
- Live Vaccines
- Heart Medications
Warnings & Precautions
Here are the key warnings and precautions for using Vivitra 150 mg (trastuzumab):
1. Cardiotoxicity (Heart Damage)
- Risk of heart failure, especially with prior anthracycline use (like doxorubicin). Monitor left ventricular ejection fraction (LVEF) before and during treatment. Do not use in patients with significant heart dysfunction unless benefits outweigh risks.
2. Infusion-Related Reactions
- May cause fever, chills, nausea, hypotension, bronchospasm, or anaphylaxis. Usually occurs during the first infusion—monitor closely and premedicate if needed.
3. Pulmonary Toxicity
- Risk of interstitial lung disease, pneumonitis, or acute respiratory distress syndrome (ARDS). Discontinue immediately if serious lung symptoms develop.
4. Embryo-Fetal Toxicity
- Can cause birth defects or fetal harm. Women of childbearing potential should use effective contraception during treatment and for 7 months after the last dose.
5. Severe Neutropenia and Infections
- When used with chemotherapy, risk of serious infections increases due to bone marrow suppression.
6. Use in Pregnancy and Lactation
- Not recommended during pregnancy or breastfeeding.
7. Pre-existing Lung or Heart Disease
- Use with extreme caution in patients with known heart or lung conditions.
8. Close Supervision During Infusion
- Emergency equipment and medications (e.g., epinephrine, antihistamines) should be available during administration.
Safety Advice
- Report any breathing difficulties, chest pain, or swelling immediately.
- Avoid pregnancy during treatment; use contraception for 7 months after.
- Do not breastfeed during treatment and for 7 months post-treatment.
- Avoid live vaccines during treatment due to weakened immune system.
- Practice good hygiene and avoid exposure to infections or sick individuals.
- Consult doctor about all medications to avoid dangerous interactions.
Frequently Asked Questions
1. Can I breastfeed while on treatment with Vivitra 150mg Injection?
Ans. No, since tends to pass into breast milk, it is unsafe to breastfeed. Hence, It is advised not to breastfeed for a minimum of 7 months after the treatment with Vivitra Injection.
2. How does Vivitra Injection works on my body?
Ans. Vivitra Injection is a monoclonal antibody. It works by blocking the actions of certain cellular proteins (HER2) that triggers cancer cell formation. It also blocks various downstream cell signalling pathways that trigger cancer growth within the body. As a result, it reduces cancer formation and prevents it further growth within the body.
3. Can Vivitra Injection cure cancer?
Ans. The cure rate of cancer depends upon the severity of the disease. However, Vivitra Injection acts by preventing the abnormal growth and multiplication of cancer cells in the body, which may help in curing cancer completely.
4. Can the use of Vivitra Injection cause hair loss?
Ans. Hair loss is one of the common side effects of receiving Vivitra Injection. If it bothers you, consult your doctor for advice.
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