Bryxta 400mg Bevacizumab Injection 16ml

Introduction to Bryxta 400 mg Injection 16ml

Bryxta 400mg injection is a medication used primarily in the treatment of certain types of cancer. The active ingredient in Bryxta is Abiraterone acetate, a drug that interferes with hormone production. Abiraterone works by inhibiting the enzyme CYP17A1, which is crucial for the production of androgens (male hormones) that can stimulate the growth of prostate cancer cells.

This injection is commonly prescribed for men with castration-resistant prostate cancer, a type of prostate cancer that continues to progress despite hormonal treatments. Bryxta 400mg is used in combination with a corticosteroid to enhance its effectiveness and help manage the cancer more effectively.

The medication is administered via intravenous injection, typically in a clinical setting. The dosing regimen and frequency depend on the specific treatment plan established by the healthcare provider, considering factors such as the stage of cancer and the patient’s overall health.

Uses of Bryxta 400mg 16ml

• Glioblastoma multiforme (brain cancer)
• Persistent, recurrent, or metastatic breast cancer
• Metastatic cervical cancer
• Advanced kidney cancer
• Metastatic colorectal cancer
• Advanced non-small-cell lung cancer
• Liver Cancer- Hepatocellular carcinoma
• Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer

How Does Bryxta 400 Works?

Bryxta 400 mg Injection has an active ingredient; Bevacizumab, anti-angiogenic medication. Bevacizumab is a form of recombinant humanized monoclonal antibody which blocks angiogenesis by blocking a protein called vascular endothelial growth factor A (VEGF-A). This stops the formation of blood vessels which bring oxygen & nutrients to cancerous cells. VEGF-A is a type of growth factor protein that stimulates angiogenesis in a range of diseases, especially in cancer.

Side Effects of Bryxta 

Common Side Effects

• Joint Pain
• Hot Flashes
• Nausea and Vomiting
• Diarrhea
• Elevated Liver Enzymes
• Appetite Loss
• Edema

Serious Side Effects

• Severe Liver Damage
• Adrenal Insufficiency
• Heart Problems
• Severe High Blood Pressure
• Bone Pain or Fractures
• Severe Fatigue or Weakness

Dosage of Bryxta 400

Bryxta 400 mg Injection contains an active ingredient, Bevacizumab, which is used in the treatment of Cancer of colon & rectum, Non-small cell lung cancer, Brain tumor, Kidney cancer, Ovarian Cancer, Glioblastoma Multiforme, Cervical cancer, Peritoneal Cancer, Fallopian Tube Cancer.

This medicine is obtainable in different substitutes & strengths & has got to be purchased or taken on doctor’s prescription only. You must talk about with your physician for adjustment of dosage & time of the medicine since age & severity of the disease differ from person to person, and this can only be finest judged by your doctor.

Adults are advised to take Bryxta 400 mg Injection at a fixed time with or without food as instructed by your Doctor. You must take Bryxta 400 mg Injection regularly on time for better results.

Other Dosages of Bryxta

• Bryxta 100mg Injection 4ml

Storage

• Store in a refrigerator at 2°C to 8°C (36°F to 46°F).
• Keep it in the original outer carton to protect from light.
• Do not shake the vial — shaking can damage the protein medicine.
• Always inspect the vial visually before use: the solution should be clear to slightly opalescent, colorless to pale brown, and free of visible particles.
• After diluting Bryxta in sterile saline, it should ideally be used immediately.

Warnings & Precautions 

1. Severe Bleeding (Hemorrhage):

• Can cause serious bleeding (e.g., nosebleeds, coughing up blood, gastrointestinal bleeding). Stop treatment if severe bleeding happens.

2. Gastrointestinal (GI) Perforation:

• Rare but serious — can cause a hole in the stomach, intestines, or bowel. Look out for severe stomach pain or fever.

3. Impaired Wound Healing:

• Bryxta can delay healing or cause surgical wounds to open. Should be stopped at least 28 days before surgery and restarted only after proper healing.

4. Blood Clots (Arterial and Venous Thrombosis):

• Increased risk of heart attack, stroke, or deep vein thrombosis. Be cautious if there’s a history of clotting issues.

5. Ovarian Failure:

• In women, Bryxta can cause hormonal changes or infertility. Important for young women to discuss fertility preservation before starting.

6. Lung Bleeding (especially in lung cancer patients):

• Can be fatal; coughing up blood is a serious warning sign.

7. Brain Condition (RPLS – Reversible Posterior Leukoencephalopathy Syndrome):

• Rare but serious; symptoms include headache, seizures, confusion, vision problems.

8. Allergic (Hypersensitivity) Reactions:

• Including life-threatening reactions (anaphylaxis). Emergency treatment might be needed if this occurs.

Safety Advice

• Avoid Unnecessary Sun Exposure
• Monitor for Clotting Risks
• Avoid Smoking and Alcohol
• Avoid Certain Vaccines
• Regular Medical Check-ups

FAQs – Frequently Asked Questions

1. What is Bryxta 400mg Injection Used for?

Bryxta 400mg Injection is used in adult patients to treat metastatic cancer in large bowel (colon/rectum), breast, kidney, and lungs. It is also used to treat recurrent advanced epithelial ovarian, fallopian tube/primary peritoneal cancer, and or persistent/recurrent/metastatic cervical cancer in affected individuals.

2. How Bryxta 400mg Injection Works?

Bryxta 400mg Injection works by reducing microvascular growth of Tumour blood vessels which leads to reduced blood flow to the Tumour cells resulting in its death thus treating the disease and preventing its spread to other parts of the body in affected individuals.

3. How Bryxta 400mg Injection is Administered?

Bryxta 400mg Injection will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will determine the correct dose and duration for you based upon your age, body weight and disease condition.