Isentress 400mg Tablet

Introduction to Isentress 400 mg Tablet

Isentress 400mg is manufactured by MSD Pharmaceuticals India Pvt. Ltd. It is a brand name for the medication Raltegravir, which is used in the treatment of HIV infection.

Uses of Isentress 400 mg 

Isentress 400 mg tablets, containing the active ingredient Raltegravir, are primarily used for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 2 kg. Here are the key uses of Isentress 400 mg:

• HIV infection
• First-line Treatment
• Treatment-Experienced Patients
• Pediatric HIV-1 Infection
• Combination Therapy
• Maintenance Therapy

How Does Isentress 400 Works?

Isentress 400 mg Tablet has an active ingredient; Raltegravir, an antiviral medication which prevents the increase of the virus in human cells. This stops the virus from producing new viruses & clears up your infection. Raltegravir (as an integrase inhibitor) targets integrase, an HIV enzyme which integrates the viral genetic material into human chromosomes, a significant step in the pathogenesis of HIV. This drug is metabolized away via Glucuronidation.

Side Effects of Isentress 400

Common Side Effects

• Headache
• Nausea
• Diarrhea
• Fatigue
• Insomnia
• Dizziness
• Rash
• Elevated Liver Enzymes

Serious Side Effects 

• Severe Skin Reactions
• Hypersensitivity Reactions
• Liver Problems
• Muscle Problems
• Immune Reconstitution Syndrome
• Changes in Mood or Behavior
• Lactic Acidosis
• New or Worsening Kidney Problems

Rare Side Effects

• Pancreatitis
• Blood Disorders
• Neurological Symptoms
• Metabolic Disorders
• Allergic Reactions
• Vision Changes

Dosage of Isentress 400 mg

Isentress 400 mg Tablet contains an active ingredient, Raltegravir, which is used in the treatment of HIV infection. This medicine is available in different substitutes & strengths & has got to be purchased or given on doctor’s prescription only. You must consult your physician for adjustment of dosage & time of the medicine because age and severity of the disease differ from person to person and it can only be best judged by your doctor.

Adults are advised to take Isentress 400 mg Tablet at a fixed time with or without food as instructed by your Doctor. You must take Isentress 400 mg Tablet regularly on time for better results.

How to Manage Side Effects?

• Consult Your Doctor: If you experience any side effects while taking Isentress 400, talk to your doctor immediately.
• Follow Prescribed Dosage: Take Isentress 400 as prescribed by your doctor. Do not exceed the recommended dosage.
• Inform Your Doctor: Before taking Isentress 400, inform your doctor about any pre-existing medical conditions, medications, or supplements you are currently taking.
• Take with Food: If Isentress 400 causes stomach upset, taking it with food may help alleviate this side effect.
• Stay Hydrated: Ensure you stay well-hydrated by drinking plenty of water, unless otherwise instructed by your healthcare provider.
• Monitor Blood Tests: Your doctor may recommend regular blood tests to monitor your liver function, kidney function, and other potential side effects.

Warning & Precautions

• Allergy
• Kidney/ Liver disease
• You must not take this medicine if you are pregnant, planning to conceive or breastfeeding
• Isentress 400 mg Tablet is not recommended for use in children under 3 years of age
• You must not drive or operate heavy machinery at the same time as taking this medicine as it may cause dizziness
• You must use effective contraception while taking Isentress 400 mg Tablet & 12 weeks after stopping it
• You must regularly get your blood tests done to monitor your blood cells, liver and kidney function, and electrolyte levels during treatment with this medicine
• Always consult with your medical doctor straight away to get the best possible treatment if you are observing any of the above-mentioned conditions.

Safety Advice

• Prescription Only: Isentress 400 is a prescription medication and should only be taken under the supervision of a qualified healthcare provider.
• Medical Supervision: Take Isentress 400 only as prescribed by your doctor. Follow their instructions regarding dosage and duration of treatment.
• Allergy Check: Inform your doctor about any known allergies to Raltegravir or any other medications before starting Isentress 400.
• Inform Your Doctor: Before starting Isentress 400, inform your doctor about your complete medical history, including any pre-existing medical conditions or other medications you are taking.

Frequently Asked Questions

1. Is Raltegravir a protease inhibitor?

Ans. No. Raltegravir is an anti HIV drug. It does not have any known inhibitory effect on enzyme protease.

2. How long do I need to take Isentress?

Ans. Isentress is typically used as a long-term treatment for HIV-1 infection. It’s important to continue taking the medication as prescribed by your healthcare provider, even if you feel well, to maintain viral suppression and reduce the risk of HIV-related complications.

3. What should I do if I miss a dose of Isentress?

Ans. If you miss a dose of Isentress, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take double doses to make up for a missed dose.

4. Where can I get more information about Isentress?

Ans. For more information about Isentress, including specific dosing guidelines, potential side effects, and interactions, consult your healthcare provider or pharmacist. They can provide personalized advice based on your medical history and individual needs.