Abevmy 400mg/16mL Injection

Introduction to Abevmy 400mg Injection

Abevmy 400mg Injection contains Bevacizumab which belongs to the group of medicines called Antineoplastic agents. It is used in adult patients with Fluoropyrimidine (chemotherapy medicine) to treat metastatic cancer in large bowel (colon or rectum).  It is also used with Paclitaxel/ Capecitabine to treat metastatic breast cancer in adult patients.

Abevmy 400mg Injection is used with chemotherapy regimen containing Platinum to treat advanced non-small cell lung cancer without epidermal growth factor receptor (mutated protein responsible to cause cancer in a cell) and with Erlotinib (chemotherapy medicine) to treat metastatic non-small cell lung cancer with epidermal growth factor receptor (in cancer cells) in adult patients.

Abevmy 400mg Injection is not recommended for use if in patients allergic to Bevacizumab, Chinese Hamster Ovary (CHO) cell products, and/or other recombinant human/humanized antibodies. It is also not recommended for use in patients who had recently undergone major operation/surgery.

Uses of  Abevmy 400 mg

• Cancer Treatment (Colorectal Cancer)
• Non-Small Cell Lung Cancer (NSCLC)
• Metastatic Renal Cell Carcinoma
• Ovarian Cancer
• Glioblastoma (Brain Cancer)
• Cervical Cancer
• Other Solid Tumors

How Does Abevmy 400 Works? 

Abevmy 400mg Injection works by reducing microvascular growth of Tumour blood vessels which leads to reduced blood flow to the Tumour cells resulting in its death thus treating the disease and preventing its spread to other parts of the body in affected individuals.

Side Effects of  Abevmy

Common Side Effects

• Constipation, loss of appetite
• Fever
• Eye problems (such as increase in production of tears)
• Changes in speech/sense of taste
• Runny nose
• Loss of body weight
• Nose bleeds

Serious Side Effects

• Severe Allergic Reactions
• High Blood Pressure
• Bleeding Problems
• Heart Problems
• Gastrointestinal Perforation
• Kidney Problems
• Protein in Urine (Proteinuria)

Dosage of  Abevmy 400 mg

Abevmy 400mg Injection contains an active ingredient, Bevacizumab, which is used in the treatment of Cancer of colon & rectum, Non-small cell lung cancer, Brain tumor, Kidney cancer, Ovarian Cancer, Glioblastoma Multiforme, Cervical cancer, Peritoneal Cancer, Fallopian Tube Cancer.

This medicine is obtainable in different substitutes & strengths & has got to be purchased or taken on doctor’s prescription only. Adults are advised to take Abevmy 400mg Injection at a fixed time with or without food as instructed by your Doctor. You must take Abevmy 400mg Injection regularly on time for better results.

Other Dosages of Abevmy

• Abevmy 100mg/4ml Injection

How To Manage Side Effects? 

• Monitor blood pressure regularly with doctor.
• Report severe allergic reactions immediately for intervention.
• Avoid bleeding risks; manage cuts carefully.
• Inform doctor about heart-related symptoms immediately.
• Stay hydrated and monitor kidney function regularly.
• Perform routine liver function tests as prescribed.
• Follow doctor’s instructions on proteinuria management.

Warnings & Precautions 

1. Blood Pressure Monitoring:

• Abevmy may cause high blood pressure (hypertension). Regular monitoring is necessary, and antihypertensive treatment may be required to manage elevated blood pressure.

2. Risk of Bleeding:

• Abevmy increases the risk of serious bleeding, including gastrointestinal, nosebleeds, or heavy bleeding. Inform your doctor of any bleeding disorders before treatment.

3. Gastrointestinal Perforation:

• Abevmy can increase the risk of gastrointestinal perforation (holes in the digestive tract), which requires immediate medical attention if abdominal pain or other symptoms occur.

4. Heart Health:

• It may cause heart problems, including heart failure. If you experience symptoms like shortness of breath, swelling in the legs, or chest pain, seek medical care immediately.

5. Kidney Function:

• Abevmy can affect kidney function. Kidney function should be monitored, especially if you have pre-existing kidney issues or if symptoms like swelling or changes in urination occur.

6. Liver Issues:

• The medication may affect liver function, causing jaundice or abnormal liver tests. Liver function tests should be performed regularly during treatment.

7. Pregnancy and Breastfeeding:

• Abevmy should not be used during pregnancy or breastfeeding. It may harm the fetus or infant. Ensure you are not pregnant before starting treatment.

Safety Advice

• Prescription Only
• Inform Your Doctor
• Pregnancy and Breastfeeding
• Blood Pressure Monitoring
• Risk of Bleeding
• Infection Risk
• Avoid Vaccines

FAQs – Frequently Asked Questions

1. What is Abevmy 400mg Injection used for?

Abevmy 400mg Injection is used in adult patients to treat metastatic cancer in large bowel (colon/rectum), breast, kidney, and lungs. It is also used to treat recurrent advanced epithelial ovarian, fallopian tube/primary peritoneal cancer, and/or persistent/recurrent/metastatic cervical cancer in affected individuals.

2. How Abevmy 400mg Injection works?

Abevmy 400mg Injection works by reducing microvascular growth of Tumour blood vessels which leads to reduced blood flow to the Tumour cells resulting in its death thus treating the disease and preventing its spread to other parts of the body in affected individuals.

3. How Abevmy 400mg Injection is administered?

Abevmy 400mg Injection will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will determine the correct dose and duration for you based upon your age, body weight and disease condition.